Results 91 to 100 of about 2,388,447 (384)

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

FEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona, Carlo M. Bergamini, Carlo Ferrari, Stefano Volinia, Nicoletta Bianchi   +4 more
wiley   +1 more source

The impact of the COVID-19 pandemic on hospital admissions for psychiatric disorders: results from the multicentre study on the Italian population “COVID-19 and Mental Health” (CoMeH)

BMC Psychiatry
Aim To evaluate the impact of the COVID-19 pandemic on hospital admissions for psychiatric disorders, with a focus on the patients’ socioeconomic and demographic characteristics and/or the diagnostic group and type of admission.
Massimiliano Aragona, Martina Ventura, Roberta Ciampichini, Anteo Di Napoli, Valeria Fano, Sara Leone, Martina Pacifici, Claudio Rosini, Caterina Silvestri, Fabio Voller, Alberto Zucchi, Christian Napoli, Alessio Petrelli   +12 more
doaj   +1 more source

Effect of an equipment-behavior change intervention on handwashing behavior among primary school children in Kenya: the Povu Poa school pilot study

BMC Public Health, 2019
Background Handwashing prevalence in schools in Kenya is low due to lack of access to water and soap and lack of drive for handwashing. Soapy water made from detergent powder is an inexpensive alternative to bar soap and disgust and social norms change ...
Wit Wichaidit, Rachel Steinacher, Jemima Akinyi Okal, Jaynie Whinnery, Clair Null, Katarzyna Kordas, Jihnhee Yu, Amy J. Pickering, Pavani K. Ram   +8 more
doaj   +1 more source

Trends and geographic variability in gender inequalities in child mortality and stunting in India, 2006–2016

Maternal and Child Nutrition, 2021
Gender disparities in child undernutrition and mortality in India have been a topic of interest for a long time, but little is known on trends or geographic variability in recent periods.
Harold Alderman, Phuong Hong Nguyen, Lan Mai Tran, Purnima Menon   +3 more
doaj   +1 more source

Poverty: A State of Extremes [PDF]

, 2006
New York was the only state where both poverty and income exceeded national levels in 2005, with 13.8% of residents living in poverty and a median household income of $49,480.

core   +1 more source

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

Molecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia, Anouk C. de Jong, Lisanne F. van Dessel, Vanja de Weerd, Corine Beaufort, Jean Helmijr, José Alberto Nakauma‐González, Job van Riet, Paul Hamberg, Daniel Vis, Michiel S. van der Heijden, Nick Beije, Martijn P. Lolkema, Teoman Deger, Saskia M. Wilting, Ronald de Wit, Maurice P. H. M. Jansen, John W. M. Martens   +17 more
wiley   +1 more source

Talking About Poverty in a Jobs and Economy Framework [PDF]

, 2011
Reducing poverty substantially is not a small project. Unfortunately, only 1 percent of Americans point to "poverty" when asked about the most important problems facing the nation.
Shawn Fremstad
core  

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Building new social contracts: a critical review of ideas and actions to fulfill African aspirations through education

National Accounting Review
This article proposes a theoretical framework for constructing a new social contract through education based on three levers—affordability, accessibility, and applicability—focusing on Africa.
Sweta C. Saxena, Giuseppe Tesoriere, Syed T. Ahmed, Wafa Aidi   +3 more
doaj   +1 more source