Results 91 to 100 of about 2,092,140 (361)

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Who is Living in Poverty and Why? [PDF]

open access: yes, 2010
In thinking about poverty, it is common to focus on those places and populations where the poverty rate is the highest, where poverty is the most concentrated and visible.
Magavern, Sam
core   +1 more source

Socioeconomic inequalities in mortality among Italian and immigrant residents: A longitudinal population-based study

open access: yesJournal of Migration and Health
Background: A socioeconomic mortality gradient, favourable to the most advantaged social groups, has been documented in high migratory pressure (HMPCs) and highly developed countries, including Italy.
Martina Ventura   +6 more
doaj   +1 more source

Use of a mobile application for Ebola contact tracing and monitoring in northern Sierra Leone: a proof-of-concept study

open access: yesBMC Infectious Diseases, 2019
Background The 2014–2016 Ebola epidemic in West Africa was the largest Ebola epidemic to date. Contact tracing was a core surveillance activity. Challenges with paper-based contact tracing systems include incomplete identification of contacts, delays in ...
Lisa O. Danquah   +8 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

U.S., Midwest Struggling With Stubborn Economic Recovery: 2010 Data Release from the U.S. Census Bureau's Current Population Survey, Annual Social & Economic Supplement [PDF]

open access: yes, 2011
The newly released poverty data from the U.S. Census Bureau's Current Population Survey provide a glimpse of the ongoing impacts of the Great Recession for millions of individuals and families.

core  

Role of the Skin Immune System in Wound Healing

open access: yesCells
Wound healing is a dynamic and complex process, characterized by the coordinated activities of multiple cell types, each with distinct roles in the stages of hemostasis, inflammation, proliferation, and remodeling. The cells of the immune system not only
Angela Cioce   +3 more
doaj   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Shedding light on quality of care: a study protocol for a randomized trial evaluating the impact of the Solar Suitcase in rural health facilities on maternal and newborn care quality in Uganda

open access: yesBMC Pregnancy and Childbirth, 2019
Background Continued progress in reducing maternal and newborn morbidity and mortality in low-income countries requires a renewed focus on quality of delivery care.
Slawa Rokicki   +3 more
doaj   +1 more source

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