Results 101 to 110 of about 816,124 (307)
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
, 2009 This report focuses on the relative poverty rate of Irish elderly, and aims to study the connection between potential changes to the state pension system and such poverty rates. The majority of Irish elderly depend in fact almost exclusively on the state
O’Donoghue, Cathal, Baroni, Elisa
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Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Tackling poverty comprehensively: effectively tackling social exclusion: the Irish experience
, 1999 We,in Ireland, are now at a key moment in our history. We are faced by a period of extraordinarily rapid and largely positive political, economic, social, cultural and demographic change. This poses us with a major choice or challenge. Will we use the
Frazer, Hugh
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Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Towards a policy for combating poverty amongst women
, 1990 This policy document on women and poverty is the culmination of three years of work on the issue by the Agency. It draws on both the experience of local women's projects in marginalised communities and research and analysis which the Agency has ...
Combat Poverty Agency (CPA)
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Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Report on combat poverty led consultation process for people living in vulnerable circumstances
, 2006 In the context of its role in supporting consultation on the National Action Plan against Poverty and Social Inclusion 2006-2008 (NAP/Inclusion), the Combat Poverty Agency undertook to organise a consultation process focusing on the poverty issues ...
Combat Poverty Agency
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Combat Poverty Agency annual report 1996 [PDF]
, 1996 This report describes the work undertaken by the Agency in the past year to reduce persistent poverty and social exclusion. The Strategic Plan 1996·98 provides the framework for this work.
Combat Poverty Agency (CPA)
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