Results 91 to 100 of about 612,590 (256)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

The role of early childhood care and education – an anti-poverty perspective

open access: yes, 2008
The remit of this paper is to explore the role of early childhood care and education from an anti-poverty perspective through considering the child outcome ‘child poverty’ and the potential benefits of early childhood services.
Hayes, Nóirín Dr.
core  

Rights-Based Approaches to Food Poverty in Ireland [PDF]

open access: yes, 2012
In Ireland food poverty has emerged as an increasingly important issue on the social policy agenda. The reasons for this include the changing understanding of the nature of food poverty, its causes, dimensions and the development of solutions, as well as
O'Connor, Deirdre   +2 more
core   +1 more source

From cercariae to chronic inflammation: understanding schistosome infection and host immune responses

open access: yesFrontiers in Immunology
Schistosomiasis is a parasitic disease caused by trematodes of the genus Schistosoma, typically found in tropical and subtropical freshwater environments.
Alessandra Torsello   +5 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Moving Out of Poverty : Volume 2. Success from the Bottom Up

open access: yes, 2009
The global moving out of poverty study is unique in several respects. It is one of the few large-scale comparative research efforts to focus on mobility out of poverty rather than on poverty alone.
Narayan, Deepa   +2 more
core   +1 more source

Socioeconomic inequalities in mortality among Italian and immigrant residents: A longitudinal population-based study

open access: yesJournal of Migration and Health
Background: A socioeconomic mortality gradient, favourable to the most advantaged social groups, has been documented in high migratory pressure (HMPCs) and highly developed countries, including Italy.
Martina Ventura   +6 more
doaj   +1 more source

Use of a mobile application for Ebola contact tracing and monitoring in northern Sierra Leone: a proof-of-concept study

open access: yesBMC Infectious Diseases, 2019
Background The 2014–2016 Ebola epidemic in West Africa was the largest Ebola epidemic to date. Contact tracing was a core surveillance activity. Challenges with paper-based contact tracing systems include incomplete identification of contacts, delays in ...
Lisa O. Danquah   +8 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Role of the Skin Immune System in Wound Healing

open access: yesCells
Wound healing is a dynamic and complex process, characterized by the coordinated activities of multiple cell types, each with distinct roles in the stages of hemostasis, inflammation, proliferation, and remodeling. The cells of the immune system not only
Angela Cioce   +3 more
doaj   +1 more source

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