Results 101 to 110 of about 2,092,140 (361)
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
At the Razor's Edge: Building Hope for America's Rural Poor [PDF]
, 2006 Hurricane Katrina exposed the poverty that lay in our midst, and although the images served to remind the country of its enduring inequality, the picture was one of urban poverty.
Leif Jensen
core
Frontiers in ImmunologySchistosomiasis is a parasitic disease caused by trematodes of the genus Schistosoma, typically found in tropical and subtropical freshwater environments.
Alessandra Torsello +5 more
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Recurrent child mortality risks and parity transition in Nigeria
Reproductive Health, 2019 Background Fertility rates remain persistently high in Nigeria, with little difference across socioeconomic groups. While the desire for large family size is culturally rooted, there is little understanding of how repeated child mortality experiences ...
Abiodun Idowu Adanikin +2 more
doaj +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
How do improved lentil varieties affect farmers’ livelihood status in central Bangladesh?
HeliyonLentil plays a crucial role in ensuring nutritional security for the majority of the people in Bangladesh. Different types of improved lentil varieties (ILVs) are being introduced in Bangladesh to enhance the production, productivity, and area coverage ...
Monira Sultana +4 more
doaj +1 more source
Subjective well-being povertyvs. Income poverty and capabilities poverty?
Journal of Development Studies, 2006 Abstract The conventional approach of economists to the measurement of poverty is to use measures of income or consumption. This has been challenged by those who favour broader criteria, such as fulfilment of ‘basic needs’ and the ‘capabilities’ to be and to do things of intrinsic worth.
Kingdon, G, Knight, J
openaire +2 more sources