Results 101 to 110 of about 2,450,637 (403)

Building new social contracts: a critical review of ideas and actions to fulfill African aspirations through education

open access: yesNational Accounting Review
This article proposes a theoretical framework for constructing a new social contract through education based on three levers—affordability, accessibility, and applicability—focusing on Africa.
Sweta C. Saxena   +3 more
doaj   +1 more source

Working to Reduce Poverty: A National Subsidized Employment Proposal

open access: yesRSF: The Russell Sage Foundation Journal of the Social Sciences, 2018
Subsidized employment programs that increase labor supply and demand are a proven, underutilized strategy for reducing poverty in the short and long term.
Indivar Dutta-Gupta   +4 more
doaj   +1 more source

Poverty and Casino Gambling in Buffalo [PDF]

open access: yes, 2011
The Buffalo Creek Casino will exacerbate Buffalo’s poverty. Casinos, especially urban casinos, attract many gamblers living at or near the poverty line, and problem or pathological gamblers often fall from the middle class into poverty.
Magavern, Sam, Mulé, Elaina
core   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser   +14 more
wiley   +1 more source

A local government authority leading action research: Impacts and replicability

open access: yesCommonwealth Journal of Local Governance, 2010
The paper explores whether the institutional model of the IDRC Colombo Focus City Project has had an impact on overcoming challenges associated with research based learning designed to influence policy and implementation processes of local government ...
Neranjana Gunetilleke
doaj   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Socioeconomic inequalities in avoidable mortality in Italy: results from a nationwide longitudinal cohort

open access: yesBMC Public Health
Background Disparities in avoidable mortality have never been evaluated in Italy at the national level. The present study aimed to assess the association between socioeconomic status and avoidable mortality.
Alessio Petrelli   +5 more
doaj   +1 more source

Poverty and its Alleviation Lessons for Nigeria [PDF]

open access: yes, 2017
The study focused on the persistent poverty status in Nigeria in spite of all the actions and activities directly and indirectly put in place to reduce it. Nigerian poverty statistics and government actions in tackling poverty were examined.
E. Uma, Kalu   +2 more
core  

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