Results 131 to 140 of about 1,962,520 (360)

A CASE OF SCURVY, WITH UNUSUAL POVERTY OF THE BLOOD. [PDF]

, 1902
JAMES ELY TALLEY
openalex   +1 more source

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source

Using the 99DOTS (directly observed treatment, short course) application for improved adherence to tuberculosis treatment in Namibia: A mixed-methods study

South African Medical Journal
Background. In Namibia, community-based directly observed tuberculosis (TB) treatment (C-DOT) has been effective for individuals living in settled villages, but it is problematic for mobile indigenous people who survive through hunting and gathering
M Claassens, P Steenkamp, R Gavioli, T Woldetsadik   +3 more
doaj   +1 more source

Poverty.Robert Hunter [PDF]

, 1905
Mary E. Richmond
openalex   +1 more source

Prosperity Threatened: Perspectives on Childhood Poverty in California [PDF]

, 2013
By the official measure, 6.1 million Californians are living in poverty -- more than at any point since the US Census started tracking state poverty. California has the highest sheer number of people living in poverty of any state in the nation and is ...
Ann O'Leary, James Barba, Rey Fuentes
core  

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

Progress and Poverty [PDF]

, 1916
G. H. Clutsam
openalex   +1 more source

The Causes of Poverty and the Scale of Poverty

, 2022
This topic has always been relevant because poverty is one of the main factors influencing the development of third-world countries. Poverty has a character that includes several aspects: social, economic, and political; for which poverty is not only a lack of what is financial income but can also be poverty in the denial of society's general rights ...
openaire   +1 more source

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

Molecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

Effects of Rural Poverty on the Health of California's Farmworkers [PDF]

, 1968
A. Gilbert, Paul F. O’Rourke
openalex   +2 more sources