Results 61 to 70 of about 11,568,905 (297)
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
, 2017 Understanding household livelihood strategies is pivotal to minimize rural poverty in the least developed countries like Nepal. This study is an attempt to assess livelihood strategies pursued by rural households, investigate the most remunerative ...
Shanta Paudel Khatiwada +5 more
semanticscholar +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
A Geographical Analysis of the Poverty Causes in China’s Contiguous Destitute Areas
Sustainability, 2018 One of the most critical development problems in China is the existence of a considerable number of contiguous destitute areas (also known as regional poverty), and the causes behind such regional poverty might structurally differ by geographical ...
Yuan Tian +4 more
semanticscholar +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Consumers’ willingness to pay for ethical consumption initiatives on e-commerce platforms
Journal of Integrative Agriculture, 2021 Despite China’s fast-growing e-commerce and its great achievement in promoting poverty alleviation through consumption, little is known about Chinese consumers’ online ethical consumption.
Er-peng WANG +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
International Journal of Anthropology and Ethnology, 2021 The incidence of poverty in three of China’s provinces (Qinghai, Guizhou and Yunnan) and five of its autonomous regions (Inner Mongolia, Guangxi, Tibet, Ningxia, and Xinjiang) is greater than the national average.
Yanzhong Wang, Sai Ding
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Dynamics of Poverty in Iran: Application of Panel Data in Urban and Rural Areas [PDF]
فصلنامه پژوهشهای اقتصادی ایران, 2007 Anti poverty program in Iran has started in 2001 to mitigate poverty. This paper addresses issues related to the dynamics of poverty using household panel data for urban and rural areas of Iran covering the period 2001-2003.
Mansor Zibaei, Ashan Shooshtarian
doaj