Results 81 to 90 of about 5,300,961 (303)

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Spatial spillover effect of multi-dimensional poverty in Malawi

open access: yesHumanities & Social Sciences Communications
High and persistent levels of multidimensional poverty pose a significant challenge in Malawi. Finding effective methods to eradicate poverty in all its forms remains a key policy concern.
Edson Ntodwa, Gowokani Chijere Chirwa
doaj   +1 more source

Single Mother Work and Poverty under Welfare Reform: Are Policy Impacts Different in Rural Areas? [PDF]

open access: yes
During the 1990s, employment increased and poverty declined for single mothers in rural and urban areas. Our results suggest that, holding demographics constant, changes in welfare and social policy during this decade contributed to employment increases--
Bruce Weber, Greg Duncan, Mark Edwards
core  

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

open access: yesMolecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David   +12 more
wiley   +1 more source

An Assessment of the Level, Trend, and Distribution of Multidimensional Poverty in Iran

open access: yesبرنامه‌ریزی و بودجه, 2020
An accurate, and time-based poverty measurement is crucial in future policymaking as well as assessing the impact of welfare policies implemented on poverty.
Yadollah Dadgar   +2 more
doaj  

Area-based socioeconomic factors and Human Papillomavirus (HPV) vaccination among teen boys in the United States

open access: yesBMC Public Health, 2017
Background This study is the first to examine associations between several area-based socioeconomic factors and human papillomavirus (HPV) vaccine uptake among boys in the United States (U.S.). Methods Data from the 2012-2013 National Immunization Survey-
Kevin A. Henry   +4 more
doaj   +1 more source

REGIONAL POVERTY IN MICHIGAN: RURAL AND URBAN DIFFERENCE [PDF]

open access: yes
This paper examines the relationship between the quality of local labor force and variation in regional poverty outcomes among Michigan areas. A regional poverty model is derived from the household production model for that purpose.
Schmid, A. Allan, Nizalov, Denys
core  

Understanding Changes in Poverty

open access: yes, 2014
Understanding Changes in Poverty brings together different methods to decompose the contributions to poverty reduction. A simple approach quantifies the contribution of changes in demographics, employment,
Saavedra-Chanduvi, Jaime   +6 more
core   +1 more source

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

open access: yesMolecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara   +10 more
wiley   +1 more source

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