Results 101 to 110 of about 11,568,905 (297)

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

open access: yesMolecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski   +12 more
wiley   +1 more source

The causes of regional variation in U.S. poverty: A cross-county analysis [PDF]

open access: yes
The persistence of poverty in the modern American economy, with rates of poverty is some areas approaching those of less industrialized nations, remains a central concern among policy makers. Therefore, this study uses U.S.
Dan Rickman
core  

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Spatial spillover effect of multi-dimensional poverty in Malawi

open access: yesHumanities & Social Sciences Communications
High and persistent levels of multidimensional poverty pose a significant challenge in Malawi. Finding effective methods to eradicate poverty in all its forms remains a key policy concern.
Edson Ntodwa, Gowokani Chijere Chirwa
doaj   +1 more source

An Assessment of the Level, Trend, and Distribution of Multidimensional Poverty in Iran

open access: yesبرنامه‌ریزی و بودجه, 2020
An accurate, and time-based poverty measurement is crucial in future policymaking as well as assessing the impact of welfare policies implemented on poverty.
Yadollah Dadgar   +2 more
doaj  

Area-based socioeconomic factors and Human Papillomavirus (HPV) vaccination among teen boys in the United States

open access: yesBMC Public Health, 2017
Background This study is the first to examine associations between several area-based socioeconomic factors and human papillomavirus (HPV) vaccine uptake among boys in the United States (U.S.). Methods Data from the 2012-2013 National Immunization Survey-
Kevin A. Henry   +4 more
doaj   +1 more source

Poverty, inequality, and geographic targeting: Evidence from Small-Area Estimates in Mozambique [PDF]

open access: yes
"Typical living standards surveys can provide a wealth of information about welfare levels, poverty, and other household and individual characteristics. However, these estimates are necessarily at a high level of aggregation, because such surveys usually
Simler, Kenneth R., Nhate, Virgulino
core  

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

The Effect of Economic Growth on Poverty and Income Inequality: Measurement of Pro-poor Growth in Urban and Rural Areas of Iran [PDF]

open access: yesفصلنامه پژوهش‌های اقتصادی ایران, 2007
Economic growth and poverty alleviation have been among the most important government policies in Iran for the past three decades. This paper examines the effect of economic growth on the poverty reduction in Iran using various methodologies and ...
Khosrow Piraee, Azadeh Ghana'atian
doaj  

Maximizing the benefits of transitways in areas of concentrated poverty (Research Brief)

open access: yes, 2019
This two-page research brief summarizes the highlights and findings for the research report Those Who Need It Most: Maximizing Transit Accessibility and Removing Barriers to Employment in Areas of Concentrated Poverty (CTS 19-05).Center for ...
Center for Transportation Studies
core  

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