Results 91 to 100 of about 11,568,905 (297)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Violência e desigualdade social: mortalidade por homicídios e condições de vida em Salvador, Brasil
Revista de Saúde PúblicaOBJETIVO: A relação entre pobreza e violência tem sido questionada por alguns autores. Nesse sentido, foi realizado estudo com o objetivo de analisar os diferenciais intra-urbanos de mortalidade por homicídio segundo as condições de vida. MÉTODOS: Estudo
Adriana C Macedo +3 more
doaj
NGOs and poverty issues in peri-urban areas [PDF]
Poverty reduction is the top-most element in the Millennium Development Goals (MDGs) set by the United Nations those have provided a broad way for the development planning professionals on the globe to assess their past performance in the important ...
Muhammad Haroon SIDDIQUE
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Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Intervenção comunitária e redução da vulnerabilidade de mulheres às DST/ Aids em São Paulo, SP
Revista de Saúde PúblicaOBJETIVOS: Com o aumento do número de casos notificados de Aids em mulheres, as intervenções comunitárias, que são fundamentais nesse contexto, são poucas e raramente avaliadas.
Regina Figueiredo +1 more
doaj
Remittances and poverty in Ghana [PDF]
The author uses a large, nationally representative household survey to analyze the impact of internal remittances (from Ghana) and international remittances (from African and other countries) on poverty in Ghana.
Adams, Richard H. Jr.
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Estimating Urban Poverty Consistently Across Countries
, 2022 Global poverty monitored by the World Bank for the Sustainable Development Goals (SDGs) is reported only at the national level, lacking a breakdown between urban and rural areas. A key challenge to producing
Nakamura, Shohei +3 more
core +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Poverty comparisons with absolute poverty lines estimated from survey data [PDF]
"The objective of measuring poverty is usually to make comparisons over time or between two or more groups. Common statistical inference methods are used to determine whether an apparent difference in measured poverty is statistically significant ...
Simler. Kenneth R., Arndt, Channing
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