Results 131 to 140 of about 418,010 (307)

The State of Poverty in Ohio: A Path to Recovery [PDF]

open access: yes, 2011
This annual report provides an update on the magnitude and impacts of poverty across Ohio. The report also highlights the work of Community Action Agencies in alleviating poverty while supporting the economic recovery of communities through programs on ...

core  

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

Map the Meal Gap 2016: Highlights of Findings for Overall and Child Food Insecurity [PDF]

open access: yes, 2016
In order to address the problem of hunger, we must first understand it. Feeding America undertook the Map the Meal Gap project to learn more about hunger at the local community level.

core  

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

DESIGUALDADE E POBREZA EN GALICIA NOS ANOS 2007 E 2010. COMO SE DISTRIBÚEN OS EFECTOS DA CRISE?

open access: yesRevista Galega de Economía, 2013
The aim of this work is to analyse the effects that the current economic crisis is producing on the Galician income distribution. We use three key variables: i) household disposable income, ii) household disposable income excluding the provision by ...
FERNANDO CORBELLE CACABELOS   +1 more
doaj  

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

Socioeconomic Distance as a Determinant of Female Autonomy and Child Welfare [PDF]

open access: yes
We quantify the impact of network-based learning and influence on measures of female power and child nutrition in rural India. Empowering women to have greater say in child rearing may generate greater and more lasting benefits to children than nutrition
Baylis, Katherine R., Kandpal, Eeshani
core   +1 more source

The Road Map Project: 2014 Results Report [PDF]

open access: yes, 2015
The Road Map Project's annual report card shows data on 29 indicators of student success, which are important measures related to student achievement from cradle through college.

core  

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

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