Results 141 to 150 of about 2,599,250 (332)

STRATEGY ANALYSIS FOR ACHIEVING SDGS TARGETS IN POSO REGENCY IN THE DEVELOPMENT OF THE TOMINI BAY ECONOMIC AREA

GeoEco
Poso Regency has a highly strategic geopolitical position and a very high economic potential. However, in achieving sustainable development goals, there are several indicators whose progress is relatively slow.
Sri Maryati, Harto S. Malik, Noval Sufriyanto Talani, Salahudin Olii   +3 more
doaj   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Reaching the Poor: Fine Tuning Poverty Targeting Using a 'Poverty Map'-The Case of Mozambique [PDF]

Poverty, Vulnerability, Targeting ...
San Martin, Orlando
core  

Poverty levels in Davidson County, Tennessee [PDF]

, 2006
This map displays the percentage of people per census tract living below the poverty level in Davidson County, Tennessee as determined by the United States Census Bureau in ...
Thornton, Jacob
core  

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Insights from poverty maps for development and food relief program targeting: an application to Malawi [PDF]

"Poverty mapping applies models of household welfare developed from detailed household consumption and expenditure surveys to the extensive but less detailed data from national censuses.
Benson, Todd
core  

High precision poverty maps

, 2017
Abstract: Estimating economic indicators is crucial for achieving a targeted implementation of welfare policies. However, for such policies to be effective, policy makers must have access to a detailed picture of deprivation that goes beyond aggregate estimates at the country (national) level, extending to finer geographical levels and to other domains
Esteve, A., Permanyer, I., Tzavidis, N., Köksel, P., Liu, C.   +4 more
openaire   +2 more sources

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Poverty alleviation through geographic targeting : how much does disaggregation help? [PDF]

Using recently completed"poverty maps"for Cambodia, Ecuador, and Madagascar, the authors simulate the impact on poverty of transferring an exogenously given budget to geographically defined subgroups of the population according to their relative poverty ...
Yin, Wesley, Ozler, Berk, Tomoki Fujii, Lanjouw, Peter, Elbers, Chris   +4 more
core