Comprehensive Powder Rheological Characterization of Fifteen Lactose-Based Co-Processed and Single-Component Excipients Using FT4 Powder Rheometry and European Pharmacopoeia Methods: A Multi-Parameter Comparative and Correlative Study [PDF]
PharmaceuticsBackground/Objectives: Co-processed excipients (CPEs) are designed for direct compression through particle engineering, yet comprehensive powder rheological profiles systematically comparing advanced and traditional characterization methods remain ...
Martin Röttig +4 more
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A concise summary of powder processing methodologies for flow enhancement
Heliyon, 2023 The knowledge of powder properties has been highlighted since the 19th century since most formulations focus on solid dosage forms, and powder flow is essential for various manufacturing operations.
Devanshi S. Shah +5 more
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Effect of Moisture on Powder Flow Properties of Theophylline [PDF]
Pharmaceutics, 2010 Powder flow is influenced by environmental factors, such as moisture and static electricity, as well as powder related factors, such as morphology, size, size distribution, density, and surface area.
Niklas Sandler +3 more
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Prediction of the particle size and flow characteristics of powder blends for tableting by near-infrared spectroscopy and chemometrics [PDF]
Romanian Journal of Pharmaceutical Practice, 2021 The purpose of this research was to apply near-infrared (NIR) spectroscopy in combination with chemometrics to predict particle size and flow characteristics of a meloxicam powder blends for tableting.
Rares Iovanov +2 more
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Effects of Gas Flow Rate on Powder Supplying Characteristics under the Action of Moving Wall [PDF]
Hangkong bingqi, 2022 The fluidization and transportation characteristics of powder fuel is a key to the design of fuel supply system of powder engine. In order to deeply study the fluidization characteristics of powder fuel, a numerical simulation method based on the two ...
Ren Guanlong, Sun Haijun, Xu Yihua, Lu Hongyi, Hu Xiao’an
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Understanding Carrier Performance in Low-Dose Dry Powder Inhalation: An In Vitro–In Silico Approach
Pharmaceutics, 2021 The use of physiologically based pharmacokinetic (PBPK) models to support drug product development has become increasingly popular. The in vitro characterization of the materials of the formulation provides valuable descriptors for the in silico ...
Joana T. Pinto +3 more
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International Journal of Pharmaceutics, 2022 Characterising powder flowability can be challenging when sample quantity is insufficient for a conventional shear cell test, especially in the pharmaceutical industry, where the cost of the active pharmaceutical ingredient (API) used is expensive at an early stage in the drug product development.
Deng, Tong +6 more
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Evaluation of Powder Flow Prediction by Ring Shear Testing at Low Consolidation Stresses
British Journal of Pharmacy, 2023 The development of XS-Lr0 low-stress shear cell by Dietmar Schulze (model RST-XS.s) has confirmed the necessity of assessing powder flow at low consolidation stresses for improved powder flow production (Søgaard et al.,2014).
Lujain El-Balawi +2 more
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Controlled flow of smart powders [PDF]
Physical Review E, 2008 The flow properties of powders are mainly due to the interplay of cohesive forces and intergrain frictional forces. We have experimentally investigated a "smart granular system" for which the interparticle cohesion can be tuned by a magnetic field B[over ] . We show that the rheological features of such a system can be controlled.
Lumay, Geoffroy, Vandewalle, Nicolas
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British Journal of Pharmacy, 2023 This study investigates the flow and compression behaviour of four excipients (StarTab®, MCC, Mannitol, Lactose) when combined with caffeine as a model drug for direct compression.
Sandeep Kumar
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