Results 61 to 70 of about 88,192,787 (242)

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Modelling and control of micro-combined heat and power (CHP) to optimise energy conversion and support power distribution networks [PDF]

, 2013
Climate change and continuously increasing energy prices have driven the need for low carbon and renewable energy technologies from different sectors, including the domestic sector, by installing higher energy efficiency technologies.
Samir, Karmacharya
core  

Review of Experimental Research on Supercritical and Transcritical Thermodynamic Cycles Designed for Heat Recovery Application

Applied Sciences, 2019
Supercritical operation is considered a main technique to achieve higher cycle efficiency in various thermodynamic systems. The present paper is a review of experimental investigations on supercritical operation considering both heat-to-upgraded heat and
Steven Lecompte, Erika Ntavou, Bertrand Tchanche, George Kosmadakis, Aditya Pillai, Dimitris Manolakos, Michel De Paepe   +6 more
doaj   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

Design of heat sinks for wearable thermoelectric generators to power personal heating garments: A numerical study [PDF]

, 2019
To mitigate climate change attributed to the built environments, there have been tremendous efforts to improve air conditioning systems in the buildings.
Soleimani, Zohreh, Cui, Y., Zoras, Stamatis, Ceranic, B., Shahzad, S., Zoras, S., Ceranic, Boris, Soleimani, Z., Shahzad, Sally, Cui, Yuanlong, Shahzad, Salome   +10 more
core   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Thermodynamic Modeling and Analysis of the Ratio of Heat to Power Based on a Conceptual CHP System [PDF]

, 2006
The CHP system not only produces electrical energy, but also produces thermal energy. An extensive analysis of the CHP market reveals that one of the most important engineering characteristics is flexibility. A variable heat-to-power ratio has compelling
Liu, Z., Li, X.
core  

Developing and testing a generic micro-combined heat and power model for simulations of dwellings and highly distributed power systems [PDF]

, 2008
This paper elaborates an approach to the modelling of domestic micro-combined heat and power (μ-CHP) using a building simulation tool that can provide a detailed picture of the environmental performance of both the μ-CHP heating system and the dwelling ...
Kelly, N.J., Burt, G., Clarke, J.A., Ferguson, A.   +3 more
core   +4 more sources

Dynamic characteristics analysis of power-to-heat molten salt heat storage and power generation system

Reli fadian
The dynamic models of steam generation system and power generation system are developed to study the dynamic characteristics of power-to-heat molten salt heat storage and power generation system, and the reliability of the models is validated.
HU Wenting, LIU Ming, ZHANG Shunqi, HAN Wei, YAN Junjie   +4 more
doaj   +1 more source

Combined Heat and Power System Dispatch Considering Heat Transfer Characteristics of Heat Exchangers

Zhongguo dianli, 2020
The heat transfer characteristic of heat exchangers is one of the key factors affecting the optimal dispatch of combined heat and power systems. In order to optimize the dispatch of the combined heat and power systems, a three-stage heat transfer model ...
Liming ZOU, Xiaoyan BIAN, Jianjie JIANG, Henchao WU   +3 more
doaj   +1 more source