Results 61 to 70 of about 359,584 (301)

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

An optimization model for multi-biomass tri-generation energy supply [PDF]

, 2009
In this paper, a decision support system (DSS) for multi-biomass energy conversion applications is presented. The system in question aims at supporting an investor by thoroughly assessing an investment in locally existing multi-biomass exploitation for ...
Rentizelas, A. A., Tatsiopoulos, I. P., Tolis, A.   +2 more
core   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Combined Heat and Power System Dispatch Considering Heat Transfer Characteristics of Heat Exchangers

Zhongguo dianli, 2020
The heat transfer characteristic of heat exchangers is one of the key factors affecting the optimal dispatch of combined heat and power systems. In order to optimize the dispatch of the combined heat and power systems, a three-stage heat transfer model ...
Liming ZOU, Xiaoyan BIAN, Jianjie JIANG, Henchao WU   +3 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

G-38, 39 and 40: An artist's exploration of space [PDF]

, 1984
Three experiments are described which use space processing technology in the formation of and coating of bubbles and spheres to be orbited as sculptures visible from Earth.
Coursen, C. D., Mcshane, J. W.
core   +1 more source

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

FEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

Living with helicopter noise : evaluating sound insulation techniques for domestic dwellings using real helicopters [PDF]

, 2011
Specific remedial works designed to improve sound installation and reduce the noise level produced by helicopters inside dwellings are described. The theoretical problems and practical solutions to installing high performance acoustic insulation to a ...
Kerry, G, Lomax1, C, Waddington, DC
core   +2 more sources

Electrical Tortuosities of Porous Structures Based on Triply Periodic Minimal Surfaces and Honeycombs for Power-to-Heat Systems

Energies
Power-to-heat (P2H) systems offer an efficient solution for decarbonization by facilitating the integration of renewable energy into the industrial, heating, and transport sectors.
Thorsten Ott, Volker Dreißigacker
doaj   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source