Results 111 to 120 of about 6,354,453 (315)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

La Rochelle sketchbook [picture] / [PDF]

open access: yes, 1930
Title devised by cataloguer.; Part of the John Power sketchbooks collection.; Inscriptions: "La Rochelle + spare"--In pencil on front cover.; Condition: Yellowing, soiled, stained.; Also available online at: http://nla.gov.au/nla.pic-vn6292721 ...
Power, J. J. W. (John Joseph Wardell), 1881-1943.
core  

1993 Wholesale Power and Transmission Rate Schedules. [PDF]

open access: yes, 1993
Bonneville Power Administration 1993 Wholesale Power Rate Schedules and General Rate Schedule Provisions and 1993 Transmission Rate Schedules and General Transmission Rate Schedule Provisions, contained herein, were approved on an interim basis effective
Administration, US Bonneville Power
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Norwich sketchbook / [PDF]

open access: yes, 1935
Title devised by cataloguer from inscriptions.; Part of the John Power sketchbooks collection.; Inscriptions: "Norwich"--In pencil on front cover.; Condition: Yellowing, soiled, stained.; Also available online at: http://nla.gov.au/nla.pic-vn6446899 ...
Power, J. J. W. (John Joseph Wardell), 1881-1943, artist.
core  

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Africa and figure studies sketchbook 6/ [PDF]

open access: yes, 1935
Title devised by cataloguer from inscriptions.; Part of the John Power sketchbooks collection.; Inscriptions: "Africa"--In pencil on front cover.; Condition: Yellowing, soiled, stained, tears.; Also available online at: http://nla.gov.au/nla.pic ...
Power, J. J. W. (John Joseph Wardell), 1881-1943, artist.
core  

An Integrated Strategy to Treat and Control Acid Mine Drainage from Waste Rock and Underground Workings at the Former Franklin Mine in Nova Scotia, Canada: Field Performance Monitoring

open access: yesPollutants
Acid mine drainage (AMD), which is primarily caused by the exposure of sulfidic minerals to oxygen and water during mining operations, remains a significant contributor to environmental pollution.
Christopher Power
doaj   +1 more source

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