Results 21 to 30 of about 103,541 (257)

Fiber MOPAs with high control and high power [PDF]

, 2008
High power fiber sources have reached several kilowatts of output power, and are now leading contenders for many applications. Important attractions include control, efficiency, manufacturability, and reliability.
M. S. Z. Abidin, J.-N. Maran, Nilsson, J., Abidin, M.S.Z., Maran, J.-N., Codemard, C.A., Y. Jeong, Dupriez, P., Richardson, D.J., Farrell, C., Yoo, S., S. Yoo, Payne, D.N., Jeong, Y., J. Nilsson, J. Ji, J. K. Sahu, Ji, J., C. Farrell, D. J. Richardson, C. A. Codemard, P. Dupriez, Sahu, J.K., D. N. Payne   +23 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Design of Integrated Power Amplifier Circuits for Biotelemetry Applications [PDF]

, 2006
Over the past few decades, wireless communication systems have experienced rapid advances that demand continuous improvements in wireless transceiver architecture, efficiency and power capabilities.
El-Desouki, Munir
core  

321W average power, 1GHz, 20ps 1060nm pulsed fiber MOPA source [PDF]

, 2005
Pulses from a gain-switched laser diode were amplified in a fiber MOPA system to produce in excess of 320W of average power in 20ps pulses at 1GHz repetition rate at ...
M. Ibsen, Nilsson, J., Y. Jeong, Dupriez, P., Ibsen, M., Piper, A., Richardson, D.J., M.N. Zervas, Malinowski, A., L.M.B. Hickey, J.K. Sahu, A. Piper, Jeong, Y., Hickey, L.M.B., J. Nilsson, D.J. Richardson, P. Dupriez, Sahu, J.K., A. Malinowski, Zervas, M.N.   +19 more
core   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

System modeling of CMOS power amplifier employing envelope and average power tracking for efficiency enhancement [PDF]

, 2013
textIn the past decade, there has been great motivation to improve the efficiency of power amplifiers (PAs) in handset transmitter systems in order to address critical issues such as poor battery life and excessive heat.
Tintikakis, Dimitri
core  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

FEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source