CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang +6 more
wiley +1 more source
Linearization techniques to suppress optical nonlinearity
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.This thesis is shown the implementation of the linearization techniques such as feedforward and pre-distortion feedback linearization to suppress the ...
Tabatabai, Farbod
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Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi +19 more
wiley +1 more source
A 55-65 GHz Internal Differentially Matched Silicon Power Amplifier With Spirally Folded 1:2 Balun
A 55-65-GHz CMOS high power amplifier (PA) is designed with the help of a spirally folded 1:2 balun. By this size-folded balun, balance-unbalanced conversion and high-power combination are accomplished concurrently.
Wei Ping Cao +3 more
doaj +1 more source
The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study
ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp +4 more
wiley +1 more source
Constant-bandwidth adaptive transimpedance amplifier [PDF]
A new CMOS transimpedance amplifier (TIA) with variable gain for optical fibre communication receivers is presented. The proposed configuration is realised in a low-cost digital 0.35 µm CMOS process fed from a single 1.8 V voltage supply.
MARIA TERESA SANZ PASCUAL +1 more
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RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu +21 more
wiley +1 more source
Power amplifier is used to amplify signal to desired power level and are commonly used in series of communication devices. In software defined radio and high data-rate communications, wideband power amplifier with high PAE is generally required. In this
Leonard
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T1 Over Squared Proton Density Ratio to Characterize Multiple Sclerosis Lesions
ABSTRACT Objective Differentiating remyelinated from demyelinated lesions in MS remains challenging without histological confirmation. This study introduces the T1‐to‐PD2 ratio (TPR) imaging approach and evaluates its ability to characterize MS lesions alongside other quantitative MRI (qMRI) metrics. Methods Thirty individuals with MS (mean age: 47.5 ±
Sarah J. Wright +10 more
wiley +1 more source
Chapter 5: “Nonlinear models with nonlinear Memory” in "RF Power Amplifier Behavioral Modeling"
This comprehensive and up-to-date review of nonlinear theory and power amplifier modelling techniques is a one-stop reference for engineers working in PA modelling or RF designers using such models.
J. A. LONAC +15 more
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