Results 51 to 60 of about 6,815,632 (371)

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Finding Structural Information of RF Power Amplifiers using an Orthogonal Non-Parametric Kernel Smoothing Estimator

open access: yes, 2015
A non-parametric technique for modeling the behavior of power amplifiers is presented. The proposed technique relies on the principles of density estimation using the kernel method and is suited for use in power amplifier modeling.
Handel, Peter   +3 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Electronic amplifier with power supply switching Patent [PDF]

open access: yes, 1967
Increasing power conversion efficiency of electronic amplifiers by power supply ...
Kramer, M.
core   +1 more source

Acoustic energy distribution in space around the pipe outlet

open access: yesArchives of Acoustics, 2014
The class-D power amplifiers which operate in a switched mode have become an attractive alternative of the conventional analog power amplifiers class-A, B and AB in the field of audio applications.
Zbigniew KULKA
doaj  

A multi-objective optimization based doherty power amplifier and its matching network optimization method.

open access: yesPLoS ONE, 2023
In the actual design process of traditional power amplifiers, there is a problem of being cumbersome and unable to simultaneously meet low power and saturation modes. Therefore, an improved multi-objective optimization algorithm proposed by decomposition
Jun Sun
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Arc protection system for high-power RF amplifiers [PDF]

open access: yes, 1972
Protective system prevents damage or destruction of high-power RF amplifiers by arcs which may occur in output transmission line.
Chernoff, R. C.
core   +1 more source

Two-frequency heating technique at the 18 GHz electron cyclotron resonance ion source of the National Institute of Radiological Sciences

open access: yes, 2014
The two-frequency heating technique was studied to increase the beam intensities of highly charged ions provided by the high-voltage extraction configuration (HEC) ion source at the National Institute of Radiological Sciences (NIRS).
Biri, S.   +8 more
core   +1 more source

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