Results 41 to 50 of about 3,850,866 (309)

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Microgrid power electronic converters: state of the art and future challenges

, 2009
This paper presents a review of the state of the art of power electric converters used in microgrids. The paper focuses primarily on grid connected converters.
Sharkh, S.M., Boltryk, R.J., Jamil, M., Hussain, B., Abu-Sara, M.   +4 more
core   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

An Investigation into Power from Pitch-Surge Point-Absorber Wave Energy Converters. [PDF]

, 2007
There is a worldwide opportunity for clean renewable power. The results from the UK Government's "Marine Energy Challenge" showed that marine energy has the potential to become competitive with other forms of energy.
Chaplin, R. V., Aggidis, George A.
core   +3 more sources

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Gradient System Modelling of Matrix Converters with Input and Output Filters [PDF]

, 2003
Due to its complexity, the dynamics of matrix converters are usually neglected in controller design. However, increasing demands on reduced harmonic generation and higher bandwidths makes it necessary to study large-signal dynamics. A unified methodology
Scherpen, Jacquelien M.A.,, Jeltsema, Dimitri,, Jeltsema, Dimitri, Scherpen, Jacquelien M.A., Klaassens, J. Ben, Klaassens, J. Ben,   +5 more
core   +1 more source

Power flow control in a modular converter with energy storage

IET Power Electronics
Using modularized power converters with scalable energy storage in particle accelerators can be further enhanced with controls that can be adapted to optimise different design targets, such as to minimise the front‐end stage peak current, the depth of ...
Krister Leonart Haugen, Konstantinos Papastergiou, Dimosthenis Peftitsis   +2 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Power Converters Dominated Power Systems

, 2020
The transition to a low-carbon society is the driving force pushing the traditional power system to increase the volume of non-synchronous technologies which mainly use power electronic converters (PEC) as an interface to the power network. Today, PEC is
Harold R. Chamorro, Chamorro, H. R., Francisco M. Gonzalez-Longatt, José Luis Rueda Torres, Rueda Torres, Jose Luis, Gonzalez-Longatt, Francisco, Acosta Montalvo, Martha Nohemi, Martha Nohemi Acosta   +7 more
core   +1 more source

Impact of Periodic Frequency Modulation on Power Quality of Switching Power Converter [PDF]

Journal of Electrical and Electronics Engineering, 2014
In this paper power quality of switching frequency modulated (SFM) power converters is analyzed in details. Careful attention is paid on the effect of SFM parameters on switching power converter input current total harmonic distortion (THD) and power ...
STEPINS Deniss
doaj