Results 51 to 60 of about 3,850,866 (309)

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

Optimal control and robust estimation for ocean wave energy converters [PDF]

open access: yes, 2013
This thesis deals with the optimal control of wave energy converters and some associated observer design problems. The first part of the thesis will investigate model predictive control of an ocean wave energy converter to maximize extracted power.
Abraham, Edo
core   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Linear generators for direct drive marine renewable energy converters [PDF]

open access: yes, 2003
This thesis is concerned with the development of linear generators for use as the power take off mechanism in marine renewable energy converters. Delivering significant power at the low velocities demanded by wave and tidal stream energy converters ...
Baker, Nicholas Jon
core  

Modelling of Power Converters Using Z-Transform

open access: yes, 2013
The paper introduces a novel method of analysis and modelling of power electronic converters. Z-transform, numerical series (sequences) are used for both steady and transient states investigation of converters.
Branislav Dobrucky   +3 more
core   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Stability Analysis and Control Design for Hybrid AC-DC More-Electric Aircraft Power Systems [PDF]

open access: yes, 2013
This thesis studies the stability of a more-electric aircraft (MEA) power system with hybrid converters and loads, and proposes a control design method using state feedback.
Li, Xiao
core  

Designing Energy Conversion Systems for the Next Decade

open access: yesElectronics, 2012
Sustainable growth in energy consumption requires transition to clean and green energy sources and energy systems. Environment friendly and renewable energy systems deal with electrical energy and rely on efficient electrical power converters. High power
Slobodan N. Vukosavić
doaj   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

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