Results 31 to 40 of about 2,473 (319)

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

A reduced‐switch‐count two‐phase interleaved switch‐control‐capacitor LLC converter with accurate current balancing

IET Power Electronics
In this paper, a reduced‐switch‐count two‐phase interleaved LLC converter with precise current balancing is proposed by using switching‐control‐capacitor (SCC) technology.
Xiang Zhou, Xiang Yu, Chaojie Li, Shuting Feng, Hongbo Zhao, Zhengchao Yan   +5 more
doaj   +1 more source

An improved four‐layer capacitor voltage control strategy combined with arm current control for transformerless modular multilevel converters

IET Power Electronics, 2023
In order to improve the performance of the transformerless modular multilevel converters (MMC) under AC and DC grid fault conditions, this paper proposes an improved four‐layer capacitor voltage control strategy combined with arm current control.
Dan Liu, Ping Xiong, Fan Xiao, Jinmu Lai, Xiaotong Ji, Wei Wang   +5 more
doaj   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Analysis and design of synchronous‐rectified LLC DC–DC converter for LDC of electric vehicles

IET Power Electronics
In electric vehicles (EVs), the low voltage dc‐dc converter (LDC) with synchronous rectifier switches (SRs) can be used to reduce conduction loss caused by the high load current and improve the efficiency.
Xiang Zhou, Shuting Feng, Chaojie Li, Zhengchao Yan   +3 more
doaj   +1 more source

Depth comparison of common inductor and common capacitor passive current sharing methods for multiphase LLC converter

IET Power Electronics, 2023
Common inductor (CIM) and common capacitor (CCM) passive current‐sharing methods have the advantages of simple implementation and low cost. However, there is still a lack of detailed comparative research on the two methods, which makes researchers ...
Zhifeng Sun, Qunfang Wu, Qin Wang, Lan Xiao, Jiangli Ren, Xiao Hui   +5 more
doaj   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

A non‐isolated single‐switch ultra‐high step‐up DC–DC converter with coupled inductor and low‐voltage stress on switch

IET Power Electronics
This paper presents a non‐isolated single‐switch ultra‐high step‐up (UHSU) DC–DC converter with a three‐winding coupled inductor (CI) which is utilized to achieve ultra‐high voltage gain with a small amount of duty cycle leading to low conduction losses ...
Ali Nadermohammadi, Mohammad Maalandish, Ali Seifi, Pouya Abolhassani, Seyed Hossein Hosseini, Murtaza Farsadi   +5 more
doaj   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

An asymmetrical quadruple active bridge series resonant DC–DC converter for modular solid‐state transformers

IET Power Electronics
The DC–DC conversion stage of a three‐stage solid‐state transformer is the most challenging due to the combination of high power, medium voltage, and medium frequency. This combination also causes most of the losses in the DC–DC stage.
Saeid Khani, Seyed Hossein Hosseini, Mehran Sabahi   +2 more
doaj   +1 more source