Results 51 to 60 of about 715,335 (264)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

MODELING AND SIMULATION OF VSC-HVDC WITH DYNAMIC PHASORS

Electrica, 2008
A novel dynamic phasors method to model voltage sources converter based HVDC (VSC-HVDC) transmission system is proposed in this paper. This approach is based on the time-varying Fourier series coefficients of the system variables, and focused on the ...
Wei YAO, Jinyu WEN, Shijie CHENG
doaj   +2 more sources

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Optimization model for distributed energy trading based on a market value allocation mechanism in the electricity spot market

Frontiers in Energy Research
This study proposes a novel distributed energy trading market model with a value distribution mechanism to optimize the allocation and transactions of distributed energy resources (DERs).
Baohua Hu, Baohua Hu, Sheng Ding, Sheng Ding, Zhaoyang Xu, Zhaoyang Xu, Xueting Cheng, Xueting Cheng, Liangliang Zhu, Liangliang Zhu, Yueshuang Bao, Yueshuang Bao, Kui Wang, Kui Wang   +13 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

A Simple but Powerful Measure of Market Efficiency [PDF]

SSRN Electronic Journal, 2018
We construct a simple measure to quantify the level of market efficiency. We apply this measure to investigate the level of market efficiency and analyze its variation over time. The main contribution of the new measure is that it makes it easy to compare market efficiency across assets, time, regions, and data frequencies.
Tran, Vu Le, Leirvik, Thomas
openaire   +2 more sources

Quantitative stability analysis of Grid-Following inverter with Grid-Supporting control and stability enhancement method based on Multi-Voltage feedforward

International Journal of Electrical Power & Energy Systems
Grid-following inverters with grid-supporting control (GFLI-GSC) can provide inertia and voltage support to the grid, but GSC degrades their stability under weak grid.
Song Zhang, Zhiwei Xie, Yandong Chen, Zili Wang, Wenhua Wu, Qianyuan Li   +5 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Thermodynamic Efficiency at Maximum Power [PDF]

Physical Review Letters, 2005
We show by general arguments from linear irreversible thermodynamics that for a heat engine, operating between reservoirs at temperatures T0 and T1, T0 >or=T1, the efficiency at maximum power is bounded from above by 1-sqrt[T1/T0].
openaire   +2 more sources

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source