Results 71 to 80 of about 715,335 (264)

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

open access: yesMolecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic   +15 more
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Local anti-freezing mechanism of large-scale natural draft wet cooling towers based on drift eliminator control

open access: yesCase Studies in Thermal Engineering
Freezing is one of the important factors affecting the efficiency and safety of cooling towers in winter. The traditional anti-freezing method, which takes the increase in the outlet water temperature as an evaluation index for the anti-freezing ...
Lei Zhang   +3 more
doaj   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

An improved grid-forming control method with adaptive virtual impedance combining current limitation and transient stability improvement

open access: yesInternational Journal of Electrical Power & Energy Systems
The virtual impedance (VI) control method is widely used to limit fault current for grid-forming converter (GFMC). However, in this article, it is found that the VI deteriorates the transient synchronization stability of the GFMC under grid faults.
Xiaoping Zhou   +8 more
doaj   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Analysis and suppression method of synchronous frequency resonance for self-synchronizing voltage source inverter

open access: yesInternational Journal of Electrical Power & Energy Systems
Self-synchronizing voltage source inverter (SSVSI) can effectively improve grid frequency stability. However, the synchronous frequency resonance (SFR) inevitably exists in SSVSI.
Youze Fu   +7 more
doaj   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

Efficient Threshold Circuits for Power Series

open access: yesInformation and Computation, 1999
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Alexis Maciel, Denis Thérien
openaire   +2 more sources

Multi-Source Information Fusion for Environmental Perception of Intelligent Vehicles Using Sage-Husa Adaptive Extended Kalman Filtering

open access: yesSensors
With the rapid advancement of intelligent driving technology, multi-source information fusion has become a vital topic in the field of environmental perception.
Yibo Meng, Huifang Kong, Tiankuo Liu
doaj   +1 more source

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