Results 31 to 40 of about 955,310 (294)

Cancer Treatment: An Overview of Pulsed Electric Field Utilization and Generation

open access: yesApplied Sciences, 2023
Patients diagnosed with cancer receive different types of treatments based on the type and the level of the tumour. An emerging treatment that differs from well-developed systematic therapies (i.e., Chemotherapy, Radiotherapy, and Immunotherapy) is ...
Mahmoud A. Alshahat   +3 more
doaj   +1 more source

On convergence of the maximum block improvement method [PDF]

open access: yes, 2015
. The MBI (maximum block improvement) method is a greedy approach to solving optimization problems where the decision variables can be grouped into a finite number of blocks. Assuming that optimizing over one block of variables while fixing all others is
Li, Zhening   +2 more
core   +2 more sources

Low-Multiplicity Burst Search At The Sudbury Neutrino Observatory [PDF]

open access: yes, 2011
Results are reported from a search for low-multiplicity neutrino bursts in the Sudbury Neutrino Observatory. Such bursts could indicate the detection of a nearby core-collapse supernova explosion. The data were taken from Phase I (1999 November-2001 May),
Aharmim, B.   +109 more
core   +1 more source

Application of real‐time nonlinear model predictive control for wave energy conversion

open access: yesIET Renewable Power Generation, 2021
This article presents an approach to implement a Nonlinear Model Predictive Controller (NMPC) in real‐time with a non‐standard cost index. The proposed technique's applications are presented to maximize the energy produced by a Wave Energy Converter (WEC)
Ali S. Haider   +2 more
doaj   +1 more source

Namibia's first high performance computer

open access: yesSouth African Computer Journal, 2023
High performance computing (HPC) refers to the practice of aggregating computing power of several computing nodes in a way that delivers much higher performance than one could achieve by a typical desktop computer in order to solve large problems in ...
Jimmy Shapopi   +2 more
doaj   +1 more source

Biomedical Informatics Applications for Precision Management of Neurodegenerative Diseases [PDF]

open access: yes, 2018
Modern medicine is in the midst of a revolution driven by “big data,” rapidly advancing computing power, and broader integration of technology into healthcare. Highly detailed and individualized profiles of both health and disease states are now possible,
Jimenez-Maggoria, Gustavo   +3 more
core   +2 more sources

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

A Detailed Analysis of Contemporary ARM and x86 Architectures [PDF]

open access: yes, 2013
RISC vs. CISC wars raged in the 1980s when chip area and processor design complexity were the primary constraints and desktops and servers exclusively dominated the computing landscape.
Blem, Emily   +2 more
core   +2 more sources

Finite Computational Structures and Implementations

open access: yes, 2016
What is computable with limited resources? How can we verify the correctness of computations? How to measure computational power with precision? Despite the immense scientific and engineering progress in computing, we still have only partial answers to ...
Egri-Nagy, Attila
core   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

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