Results 71 to 80 of about 10,934,057 (300)

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Solving differential‐algebraic equations in power system dynamic analysis with quantum computing

Energy Conversion and Economics
Power system dynamics are generally modeled by high dimensional non‐linear differential‐algebraic equations (DAEs) given a large number of components forming the network.
Huynh T. T. Tran, Hieu T. Nguyen, Long T. Vu, Samuel T. Ojetola   +3 more
doaj   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

Quantum Computing in Power System Simulation

, 2008
: The concept of quantum computing has been conjectured as the next major breakthrough in computing. The basis of quantum computing, its strengths, weaknesses, and challenges are outlined.
Daniel J. Tylavsky, G. T. Heydt
core  

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Fulfilling the vision of autonomic computing [PDF]

, 2010
Efforts since 2001 to design self-managing systems have yielded many impressive achievements, yet the original vision of autonomic computing remains unfulfilled.
Nixon, Paddy, Hinchey, Mike, Paddy Nixon (12588778), Roy Sterritt (12616153), Dobson, Simon, Mike Hinchey (12615844), Sterritt, Roy, Simon Dobson (365078), Sterritt, Roy; id_orcid, Dobson, Simon; id_orcid   +9 more
core   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

Molecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan, Beatriz Martín‐Gracia, Eva Bassols‐Citores, Krizia Sagini, Maria K. Andersen, Tuula A. Nyman, May‐Britt Tessem, Morten B. Rye, Alicia Llorente   +8 more
wiley   +1 more source

A Tale of Migration to Cloud Computing for Sharing Experiences and Observations

, 2011
Cloud computing is an emerging paradigm, which promises to make the utility computing model comprehensively implemented by using virtualization technologies.
Chauhan, Muhammad Aufeef, Muhammad Aufeef Chauhan, Babar, M. A.,, Babar, M., Chauhan, M., Ali Babar, Muhammad, Muhammad Ali Babar, Chauhan, Muhammad Aufeef,   +7 more
core   +1 more source

Heterogeneous computing power scheduling system and applications under the background of computing- network convergence

Dianxin kexue
In view of the development of computing-network convergence and computing-network infrastructure in China in recent years, the system positioning and functional architecture of heterogeneous computing power scheduling were expounded, and four key ...
Gong Hao
doaj