Results 51 to 60 of about 304,417 (312)

Epistemic Exhaustion and the Retention of Power

SSRN Electronic Journal, 2023
AbstractEpistemic exhaustion is cognitive fatigue generated by efforts to determine, retain, or communicate what one believes under conditions that make doing so especially taxing. I argue that the creation and maintenance of epistemic exhaustion is a tool that the socially and politically powerful can and do use in order to retain power.
openaire   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Experiments on plasma detachment in a V-shaped slot divertor in the DIII-D tokamak

Nuclear Fusion
Experiments in DIII-D demonstrate that the upstream plasma density to detach an un-pumped slot divertor is similar for a V-shaped and a flat-end slot, despite significantly higher neutral pressure in the V-shaped slot and in contrast to SOLPS-ITER ...
R. Maurizio, D. Thomas, J.H. Yu, T. Abrams, A.W. Hyatt, J. Herfindal, A. Leonard, X. Ma, A.G. McLean, J. Ren, F. Scotti, M.W. Shafer, G. Sinclair, H.Q. Wang, J. Watkins   +14 more
doaj   +1 more source

Exhaust heat harvesting of automotive engine using thermoelectric generation technology

Energy Conversion and Management: X, 2023
Exhaust heat recovery from internal combustion engines is growing interest to reduce fuel consumption, increase the efficiency and consequently, reduce the environmental pollution and global warming.
Md. Asaduzzaman, Md. Hasan Ali, Nahyan Ahnaf Pratik, Nafisa Lubaba   +3 more
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Calorimetry measurement for energy balance and energy distribution in WEST for L-mode plasmas

Nuclear Fusion
This paper presents the energy balance of 602 pulses from four different experimental campaigns for the WEST tokamak. Different magnetic configurations have been studied, with lower single null (LSN) and upper single null (USN) configuration with ...
J. Gaspar, J. Gerardin, Y. Corre, J. Daumas, N. Fedorczak, V. Lamaison, C. Bourdelle, G. Ciraolo, A. Ekedahl, A. Gallo, N. Rivals, E. Tsitrone, the WEST Team   +12 more
doaj   +1 more source

Carbon dioxide removal from power plant exhausts

Environment International, 1979
Abstract The various options for removing carbon dioxide (CO 2 ) from power plant exhaust gases are reviewed. An absorption-stripping system using amine solutions and dissolution of gaseous CO 2 into deep ocean waters is a feasible choice with a marginal cost of electricity below 15%.
C. Mustacchi, P. Armenante, V. Cena
openaire   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Parallel flows as a key component to interpret Super-X divertor experiments

Nuclear Fusion
The Super-X Divertor (SXD) is an alternative divertor configuration leveraging total flux expansion at the Outer Strike Point (OSP). While the extended 2-Point Model (2PM) predicts facilitated detachment access and control in the SXD configuration, these
M. Carpita, O. Février, H. Reimerdes, C. Theiler, B.P. Duval, C. Colandrea, G. Durr-Legoupil-Nicoud, D. Galassi, S. Gorno, E. Huett, J. Loizu, L. Martinelli, A. Perek, L. Simons, G. Sun, E. Tonello, C. Wüthrich, the TCV Team   +17 more
doaj   +1 more source