Results 121 to 130 of about 21,829,809 (355)
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Connections between single-factor analysis and graphical Gaussian models
, 2006 The classical single-factor model is parametrized as a graphical Gaussian model. The relationship between the classical parametrization of the single-factor model and this alternative parametrization is derived.
Smith, Peter W. F. +2 more
core
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Parallellism of power convertersfor automatic power factor correction
Electronics Letters, 1997 The modular development of a single-stage 3-phase AC-DC power converter is described. The converter offers several advantageous features.
Chung, H, Hui, SYR
openaire +2 more sources
Two stage unity power factor rectifier design
, 2004 This paper presents the design process utilised for producing a two stage isolated Unity Power Factor (UPF) rectifier. The important yet less intuitive aspects of the design process are highlighted to aid in the simplification of designing a power ...
Lister, Christopher D. +3 more
core
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Topological issues in single-phase power factor correction [PDF]
, 2001 The equipment connected to an electricity distribution network usually needs some kind of power conditioning, typically rectification, which produces a nonsinusoidal line current due to the nonlinear input characteristic. With the steadily increasing use
Grigore, Vlad
core
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Analysis of the electrical power generated by a 2 Mwp photovoltaic plant connected to the MV distribution network: Focus on the power factor [PDF]
EPJ Web of ConferencesThis article presents a case study on analyzing active and reactive power injected by a 2 MWp photovoltaic (PV) power plant to the MV distribution network.
Bouzbiba Azeddine +2 more
doaj +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source