Results 101 to 110 of about 4,597,299 (248)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Of all the Gin Joints: Harris and the Supreme Court’s Reluctant Jurisprudence on Partisanship in Redistricting [PDF]

open access: yes, 2016
As interpreted by the Supreme Court, the Fourteenth Amendment’s Equal Protection Clause protects the voting power of citizens. Thus, drawing state legislative districts resulting in dilution of citizens’ voting power may violate the Constitution. However,
Bellis, Andrew
core   +1 more source

On the prime power factorization of n!

open access: yesJournal of Number Theory, 2009
Let \(q_1,~\ldots,~q_k\) be distinct primes. For a prime \(q\) and a positive integer \(n\) let \(e_q(n)\) be the exponent of \(q\) in the factorization of \(n!\). Recently, there has been a lot of interest in studying the distribution of the numbers \(e_{q_1}(n),\ldots,e_{q_k}(n)\) in arithmetic progressions modulo \(m_1,\ldots,m_k\), respectively ...
openaire   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Nuclear physics in soft-wall AdS/QCD: Deuteron electromagnetic form factors

open access: yes, 2015
We present a high-quality description of the deuteron electromagnetic form factors in a soft-wall AdS/QCD approach. We first propose an effective action describing the dynamics of the deuteron in the presence of an external vector field.
Gutsche, Thomas   +3 more
core   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Guidelines for Weighting Factors Adjustment in Finite State Model Predictive Control of Power Converters and Drives [PDF]

open access: yes, 2009
INTERNATIONAL CONFERENCE ON INDUSTRIAL TECHNOLOGY () (.2009.VICTORIA, AUSTRALIA)Model Predictive Control with a finite control set has emerged as a promising control tool for power converters and drives.
Cortés, Patricio   +7 more
core  

Parallellism of power convertersfor automatic power factor correction

open access: yesElectronics Letters, 1997
The modular development of a single-stage 3-phase AC-DC power converter is described. The converter offers several advantageous features.
Chung, H, Hui, SYR
openaire   +2 more sources

Impact analysis of human factors on power system operation reliability

open access: yesJournal of Modern Power Systems and Clean Energy, 2018
Along with the improvement of electrical equipment reliability, people's unsafe behaviors and human errors have become one of main sources of risks in power systems.
Yingkai Bao   +5 more
doaj   +1 more source

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