Results 81 to 90 of about 3,694,906 (294)

Development and Application of Integrated Aerodynamic Protuberant Foil Journal and Thrust Bearing in Turboexpander

International Journal of Rotating Machinery, 2017
Foil bearing provides compliant support and moderate Coulomb friction for rotor-bearing system, which is conducive to stability and reliability of high speed rotating machinery.
Tianwei Lai, Yu Guo, Wei Wang, Yu Wang, Yu Hou   +4 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Measurements of the magnetic field induced by a turbulent flow of liquid metal

, 2005
Initial results from the Madison Dynamo Experiment provide details of the inductive response of a turbulent flow of liquid sodium to an applied magnetic field. The magnetic field structure is reconstructed from both internal and external measurements.
Bourgoin M., C. B. Forest, C. M. Jacobson, E. J. Spence, Forest C. B., Krause K., M. D. Nornberg, Moffatt H. K., O’Connell R., Press W. H., R. D. Kendrick, Tennekes H.   +11 more
core   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Numerical simulation on H2S distribution characteristics of tangentially coal-fired boiler under wide loads

Meitan xuebao
Air staged combustion reduces NOx emissions, but increases the H2S concentration in primary combustion zone. The excessive H2S concentration near the furnace wall is an important factor that aggravates the high-temperature corrosion of the water-cooled ...
Lei DENG, Maobo YUAN, Jiahui YANG, Lei HAN, Jiahao JIANG, Defu CHE   +5 more
doaj   +1 more source

Experimental and Numerical Investigations on the Local Direct Leakage Process of Rotary Regenerative Air Preheater

Applied Sciences, 2020
An inherent defect of the operating rotary air preheaters (RAPH) is known as leakage, which seriously hinders the efficient and safe operation of RAPH.
Hua Zhu, Dechao Li, Henglin Pu, Limin Wang, Yang He, Yufan Bu, Defu Che   +6 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Flow control valve is independent of pressure drop [PDF]

, 1965
Remote control of fluid flow in a low-power system is established by a flow control valve with a flapper and nozzle flow control.

core   +1 more source