Results 61 to 70 of about 45,151 (266)

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

An Evaluation of Predictor Variables for Photovoltaic Power Forecasting

, 2022
Accurate forecasts of the electric power generation by solar Photovoltaic (PV) systems are essential to support their vast increasing integration. This study evaluates the interdependence of 14 predictor variables and their importance to machine learning models that forecast the day-ahead PV power production.
Lennard Visser, Tarek AlSkaif, Wilfried van Sark   +2 more
openaire   +3 more sources

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Editorial: Offshore wind energy: Modeling and measurements

Frontiers in Energy Research, 2023
Xiaoli Guo Larsén, Joanna Staneva, Anna Rutgersson, Julie Lundquist   +3 more
doaj   +1 more source

Wavelet decomposition and neural networks: a potent combination for short term wind speed and power forecasting

Frontiers in Energy Research
The forecast of wind speed and the power produced from wind farms has been a challenge for a long time and continues to be so. This work introduces a method that we label as Wavelet Decomposition-Neural Networks (WDNN) that combines wavelet decomposition
Adaiyibo E. Kio, Jin Xu, Natarajan Gautam, Yu Ding, Yu Ding   +4 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Performance Study and Implementation of Accurate Solar PV Power Prediction Methods for the Nagréongo Power Plant in Burkina Faso

Energies
This study aimed to implement an effective power prediction method to support the optimal management of the 30 MW Nagréongo solar photovoltaic (PV) plant in Burkina Faso.
Sami Florent Palm, Aboubakar Gomna, Sani Moussa Kadri, Dominique Bonkoungou, Adélaïde Lareba Ouedraogo, Yrébégnan Moussa Soro, Marie Sawadogo   +6 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Comparison of Electricity Production Prediction Models Based on Meteorological Data for Photovoltaic Farms in Poland—Challenges and Problems

Solar
In response to the growing need for accurate forecasting of electricity generation from PV installations, which is crucial both for enhancing self-consumption and for balancing the power grid, this study presents a comparative analysis of selected ...
Piotr Kraska, Krzysztof Hanzel
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source