Results 71 to 80 of about 45,151 (266)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Multistep-Ahead Forecasting of Chlorophyll Concentration Based on Dynamic Collaborative Attention Network

open access: yesJournal of Marine Science and Engineering
Multistep-ahead forecasting of chlorophyll concentration is of great significance in red tide early warning systems. Existing methods often neglect the potential adverse interactions between non-predictive variables and chlorophyll while failing to fully
Lei Wang   +10 more
doaj   +1 more source

An Improved Forecasting Method for Photovoltaic Power Based on Adaptive BP Neural Network with a Scrolling Time Window

open access: yesEnergies, 2017
Due to the large scale of grid-connected photovoltaic (PV) power generation installations, accurate PV power forecasting is critical to the safe and economic operation of the electric power system.
Honglu Zhu   +4 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Comparison of Training Approaches for Photovoltaic Forecasts by Means of Machine Learning

open access: yesApplied Sciences, 2018
The relevance of forecasting in renewable energy sources (RES) applications is increasing, due to their intrinsic variability. In recent years, several machine learning and hybrid techniques have been employed to perform day-ahead photovoltaic (PV ...
Alberto Dolara   +4 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

A review of research on spatial-temporal forecasting of power load based on spatial-temporal data mining

open access: yesInternational Journal of Electrical Power & Energy Systems
Lately, in the context of global energy crisis and economic recovery after the COVID-19 epidemic, the contradiction between power supply and demand has become more prominent, showing a tight balance.
Zhanshuo Hu   +5 more
doaj   +1 more source

Infection forecasts powered by big data [PDF]

open access: yesNature, 2018
Web searches, medical records and networks of local volunteers are enabling faster control of disease outbreaks. Web searches, medical records and networks of local volunteers are enabling faster control of disease outbreaks.
openaire   +2 more sources

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

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