Results 61 to 70 of about 11,108 (308)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Dynamic Analysis of Power System with Photovoltaic Generation

open access: yesMATEC Web of Conferences, 2016
With more penetration of solar power plants, photovoltaic generation will be exerting more influences on the power system. The main purpose of this paper is to study the dynamic characteristics of the power system with photovoltaic generation.
Hsu Chia-Yu   +2 more
doaj   +1 more source

Effect of Blade Faults on the Performance Characteristics of a Vertical Axis Wind Turbine [PDF]

open access: yes, 2013
Due to the diminishing reserves of fossil fuels and increased pollution from exploitation of these fuels, the world is focusing on the renewable energy sources. Wind is being considered as one of the prime next generation energy sources.
Park, Kyooseon   +3 more
core  

Wind turbine condition assessment through power curve copula modeling

open access: yes, 2012
Power curves constructed from wind speed and active power output measurements provide an established method of analyzing wind turbine performance. In this paper it is proposed that operational data from wind turbines are used to estimate bivariate ...
Galloway, Stuart   +2 more
core   +1 more source

Probabilistic Framework for Online Identification of Dynamic Behavior of Power Systems With Renewable Generation [PDF]

open access: yes, 2018
The paper introduces a probabilistic framework for online identification of post fault dynamic behavior of power systems with renewable generation.
Papadopoulos, Panagiotis N; id_orcid   +7 more
core   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

Analysis of Neutral Point Clamped power converters in FPL systems under grid faults

open access: yes, 2022
Distribution lines are dealing with several challenges such as the increase of power consumption, the integration of renewable resources, etc. which are driving them to more intelligent grids or smart grids.
Aizpuru, Iñaki   +4 more
core   +1 more source

Testability and redundancy techniques for improved yield and reliability of CMOS VLSI circuits [PDF]

open access: yes, 1992
The research presented in this thesis is concerned with the design of fault-tolerant integrated circuits as a contribution to the design of fault-tolerant systems.
Bensouiah, Djamel Abderrahmane
core  

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