Results 61 to 70 of about 9,504 (261)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Research on short-term power load forecasting based on deep reinforcement learning with multiple intelligences

open access: yesEAI Endorsed Transactions on Energy Web
A reliable supply of power systems is critical for industry, commerce, and residential life. Improving the accuracy and reliability of short-term electricity load forecasting plays a crucial role in ensuring the satisfaction of electricity demand and ...
Tianyun Luo   +5 more
doaj   +1 more source

Design Models for Power Flow Management of a Grid-Connected Solar Photovoltaic System with Energy Storage System

open access: yesEnergies, 2020
This paper provides models for managing and investigating the power flow of a grid-connected solar photovoltaic (PV) system with an energy storage system (ESS) supplying the residential load.
Mariz B. Arias, Sungwoo Bae
doaj   +1 more source

Review of multiple load forecasting method for integrated energy system

open access: yesFrontiers in Energy Research, 2023
In order to further improve the efficiency of energy utilization, Integrated Energy Systems (IES) connect various energy systems closer, which has become an important energy utilization mode in the process of energy transition.
Yujiao Liu   +5 more
doaj   +1 more source

Model predictive load scheduling using solar power forecasting [PDF]

open access: yes2016 American Control Conference (ACC), 2016
In this paper a model is developed to solve the on/off scheduling of (non-linear) dynamic electric loads based on predictions of the power delivery of a (standalone) solar power source. Knowledge of variations in the solar power output is used to optimally select the timing and the combinations of a set of given electric loads, where each load has a ...
Abdulelah H. Habib   +2 more
openaire   +2 more sources

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Forecast-informed power load profiling: A novel approach

open access: yesEngineering Applications of Artificial Intelligence, 2020
Power load forecasting plays a critical role in the context of electric supply optimization. The concept ofload characterization and profiling has been used in the past as a valuable approach to improve forecasting performance as well as problem interpretability. This paper proposes a novel, fully fledged theoretical framework for a joint probabilistic
Óscar García Hinde   +2 more
openaire   +2 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

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