Results 61 to 70 of about 9,504 (261)
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
A reliable supply of power systems is critical for industry, commerce, and residential life. Improving the accuracy and reliability of short-term electricity load forecasting plays a crucial role in ensuring the satisfaction of electricity demand and ...
Tianyun Luo +5 more
doaj +1 more source
This paper provides models for managing and investigating the power flow of a grid-connected solar photovoltaic (PV) system with an energy storage system (ESS) supplying the residential load.
Mariz B. Arias, Sungwoo Bae
doaj +1 more source
Review of multiple load forecasting method for integrated energy system
In order to further improve the efficiency of energy utilization, Integrated Energy Systems (IES) connect various energy systems closer, which has become an important energy utilization mode in the process of energy transition.
Yujiao Liu +5 more
doaj +1 more source
Model predictive load scheduling using solar power forecasting [PDF]
In this paper a model is developed to solve the on/off scheduling of (non-linear) dynamic electric loads based on predictions of the power delivery of a (standalone) solar power source. Knowledge of variations in the solar power output is used to optimally select the timing and the combinations of a set of given electric loads, where each load has a ...
Abdulelah H. Habib +2 more
openaire +2 more sources
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Forecast-informed power load profiling: A novel approach
Power load forecasting plays a critical role in the context of electric supply optimization. The concept ofload characterization and profiling has been used in the past as a valuable approach to improve forecasting performance as well as problem interpretability. This paper proposes a novel, fully fledged theoretical framework for a joint probabilistic
Óscar García Hinde +2 more
openaire +2 more sources
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source

