From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
IGBT Real-time Junction Temperature Calculation Based on Converter Operation Data
In order to evaluate IGBT operation junction temperature of locomotive operation and provide the basis for IGBT health status and life prediction, a real-time junction temperature calculation method was proposed based on the average power loss of each ...
LI Yanyong +5 more
doaj
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
The Mechanism, Calculation and Simulation of Power Loss for IGBT Modules
In this paper, the mechanism of IGBT power loss was analyzed, the definition and calculation of the power loss were discussed based on the characteristics of conduction and switching.
WANG Yangang +4 more
doaj
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Reactive Power Optimization with Chaotic Firefly Algorithm and Particle Swarm Optimization in A Distribution Subsystem Network [PDF]
In this paper the minimization of power losses in a real distribution network have been described by solving reactive power optimization problem. The optimization has been performed and tested on Konya Eregli Distribution Network in Turkey, a section ...
Hamza Yapıcı, Nurettin Çetinkaya
doaj
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Electrical model for power losses in direct power injection
This paper introduces a study of power losses in a populated board under direct power injection (DPI), used to measure the immunity of integrated circuits to conducted continuous-wave interference. The relative contributions of all loss sources are evaluated, leading to the preeminence of conductive and dielectric losses over radiated ones, and an ...
Alaeldine, Ali +3 more
openaire +2 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Comprehensive Power Losses Model for Electronic Power Transformer
The electronic power transformer (EPT) has higher power losses than the conventional transformer. However, the EPT can correct the power factor, compensate the unbalanced current, and reduce the line power losses in the distribution network. Therefore, the higher power losses of the EPT and the consequent reduced power losses in the distribution ...
Quanyou Yue +6 more
openaire +3 more sources

