Results 71 to 80 of about 1,055,712 (266)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Power loss mechanisms in pathological tracheas

Journal of Biomechanics, 2016
The effort required to inhale a breath of air is a critically important measure in assessing airway function. Although the contribution of the trachea to the total flow resistance of the airways is generally modest, pathological alterations in tracheal geometry can have a significant negative effect.
Bates, A.J., Comerford, A., Cetto, R., Schroter, R.C., Tolley, N.S., Doorly, D.J.   +5 more
openaire   +3 more sources

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Comparative Analysis of Power Losses in the Single-Flow LS-Systems with Pump and Valve Configuration

Механика машин, механизмов и материалов, 2018
The power losses in the single-flow hydraulic LS-systems with a pump configuration (using the variable displacement LS-pump) and with a valve configuration (using the fixed displacement pump) are investigated.
Aleksander A. Hinzburh, Dmitriy L. Stasenko   +1 more
doaj  

Minimizing Power Loss Using Modified Artificial Bee Colony Algorithm

Journal of Computing Research and Innovation, 2021
Electrical energy losses are found in any part of the power system. In the power system, it is essential to minimize the real power loss in transmission lines.
Nur Azlin Ashiqin Mohd Amin, Siti Hafawati Jamaluddin, Nur Syuhada Muhammat Pazil, Norwaziah Mahmud, Norhanisa Kimpol   +4 more
doaj  

Optimal Number, Location, and Size of Distributed Generators in Distribution Systems by Symbiotic Organism Search Based Method

Advances in Electrical and Electronic Engineering, 2017
This paper proposes an approach based on the Symbiotic Organism Search (SOS) for optimal determining sizing, siting, and number of Distributed Generations (DG) in distribution systems.
Tri Phuoc Nguyen, Dieu Ngoc Vo, Tung The Tran   +2 more
doaj   +1 more source

Analysis of Critical Power Loss in a Superconductor [PDF]

Journal of Applied Physics, 1971
A critical power dissipation resulting from an oscillating magnetic field, Hp cosωt, can produce a magnetic breakdown field, Hp′ < Hc, the critical field of the superconductor. The analysis shows, for example, why the breakdown field of a superconducting microwave cavity can be well below Hc in some cases, and indicates what the functional ...
openaire   +2 more sources

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

THE LOSS OF SEXUAL POWER IN TABES DORSALIS. [PDF]

The Lancet, 1898
n ...
openaire   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source