Results 91 to 100 of about 9,415,163 (356)

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu   +15 more
wiley   +1 more source

Large hadronic power corrections or new physics in the rare decay B → K∗μ+μ−? [PDF]

open access: yes, 2017
A bstractThe well-known problem of the unknown power corrections within QCD improved factorisation leaves the interpretation of the so-called LHCb anomalies in the angular observables of B → K∗μ+μ− as an open problem.
V. Chobanova   +6 more
semanticscholar   +1 more source

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte   +10 more
wiley   +1 more source

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

open access: yesFEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi   +2 more
wiley   +1 more source

The ground states of hidden-charm tetraquarks and their radial excitations

open access: yesEuropean Physical Journal C: Particles and Fields
Inspired by the great progress in the observations of charmonium-like states in recent years, we perform a systematic analysis about the ground states and the first radially excited states of $$qc\bar{q}\bar{c}$$ q c q ¯ c ¯ (q = u/d and s) tetraquark ...
Guo-Liang Yu   +5 more
doaj   +1 more source

Physics of Rock Scour: The Power of the Bubble [PDF]

open access: yesScour and Erosion, 2010
Scour of rock downstream of high-head hydraulic structures is governed by multiphase physics of turbulent air-water mixtures impacting and eroding fractured rock. The present paper provides first of all an overview of the main physical processes and focuses on relevant break-up mechanisms of rock.
openaire   +3 more sources

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

open access: yesFEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik   +3 more
wiley   +1 more source

A dataset of a proxy variable for the poultry trade flows in China

open access: yesScientific Data, 2022
Measurement(s) poultry trade flows Technology Type(s) poultry food product Factor Type(s) poultry product • poultry consumption Sample Characteristic - Organism poultry Sample Characteristic - Environment poultry food product Sample Characteristic ...
Lingcai Kong   +5 more
doaj   +1 more source

Coordinated Research Program in Pulsed Power Physics.

open access: yes, 1984
: Work on three program elements, related to pulsed power research, is described. The program is a multi-investigator program whose main emphasis is on gaining a better understanding of repetitive opening and closing switch phenomena.
M. Kristiansen   +4 more
semanticscholar   +1 more source

The impact of frailty syndrome on skeletal muscle histology: preventive effects of exercise

open access: yesFEBS Open Bio, EarlyView.
Frailty syndrome exacerbates skeletal muscle degeneration via increased ECM deposition and myofiber loss. This study, using a murine model, demonstrates that endurance exercise attenuates these histopathological alterations, preserving muscle integrity. Findings support exercise as a viable strategy to counteract frailty‐induced musculoskeletal decline
Fujue Ji   +3 more
wiley   +1 more source

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