Results 101 to 110 of about 2,771,480 (296)
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
DEVELOPMENT OF HEATING DEVICES FOR IMPROVEMENT OF THE HEAT SUPPLY SYSTEM’S EFFECTIVENESS FOR RESIDENTIAL BUILDINGS AND CONSTRUCTIONS [PDF]
, 2018 The use of autonomous heat supply systems in housing and public utilities will reduce energy costs for 30-40%, and the total cost of heat supply by 20 - 30% compared to the heat supply from solid and liquid fuel boilers ...
FEDOROV, Sergei, SHKRABETS, Fedir
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Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
On the Estimation of the Distribution of Power Generated at a Wind Farm using Forecast Data [PDF]
, 2008 New regulations on the supply of electrical energy in Ireland have introduced a system of suppliers bidding proposals for the cost of supply for each 30 minute period of the following day.
Ramsey, David
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Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Optimization planning of new rural multi-energy distribution network based on fuzzy algorithm
Energy InformaticsWith the increasing demand for renewable energy in new rural areas, the integration and optimization of multi-energy systems such as wind and photovoltaic have become a key issue in distribution network planning.
Huanhuan Ye +5 more
doaj +1 more source
Spacecraft high-voltage power supply construction [PDF]
The design techniques, circuit components, fabrication techniques, and past experience used in successful high-voltage power supplies for spacecraft flight systems are described.
Stern, J. E., Sutton, J. F.
core +1 more source
First ATS launch set, December 6 [PDF]
, 1966 Applications Technology Satellite /ATS/ LAUNCHING, communications, power supply, control, and ground station ...
core +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Low power electromagnetic flowmeter providing accurate zero set [PDF]
, 1971 A low power, small size electromagnetic flowmeter system is described which produces a zero output signal for zero flow. The system comprises an air core type electromagnetic flow transducer, a field current supply circuit for the transducer coils and a ...
Fryer, T. B.
core +1 more source