Results 51 to 60 of about 26,199,217 (301)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

An analytical approach for power system frequency stability evaluation

IET Generation, Transmission & Distribution
Recent years have seen high penetration of renewable energies, which have significantly reduced the inertia of bulk power systems. As a result, the frequency behaviour of power systems is becoming more complex.
Zhenyao Li, Jing Li, Deqiang Gan
doaj   +1 more source

Stability Margin Index of the Receiving-End Power System Based on the Whole Process Simulation

IEEE Access
With the rapid development of the Chinese power grid, its dynamic behavior becomes increasingly complex. How to prevent voltage instability and voltage collapse at the receiving-end system has become an urgent problem at present.
Li Huang
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Frequency regulation controller for multi‐area interconnected power system

IET Generation, Transmission & Distribution
By increasing the number of electric vehicles (EVs) to achieve a less carbon environment, not only they consume power from the grid to be charged, but also do they deliver power to the grid, and this can play a significant role in load frequency control.
Sajjad Malek, Amin Khodabakhshian, Rahmat‐Allah Hooshmand   +2 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Impacts of different wind power generators on power system small signal and transient stability

, 2013
With the ever-increasing penetration level of wind power, the impacts of wind power on the power system are becoming more and more significant. Hence, it is necessary to systematically examine its impacts on the small signal stability and transient ...
Li, Sicen, Ledwich, Gerard, He, Ping, Wen, Fushuan, Xue, Yusheng   +4 more
core   +1 more source

Gradient descent based dynamic optimization for VSG dominated microgrid

The Journal of Engineering
As the integration of distributed generation units into the power grid continues to grow, the system becomes increasingly vulnerable to power fluctuations and potential failures, which significantly challenge grid stability.
Yan Li, Decheng Wang, Qun Zhang, Jian Du, Qinshan Wang, Qiong Wang   +5 more
doaj   +1 more source

Online Evaluation Method for Low Frequency Oscillation Stability in a Power System Based on Improved XGboost

Energies, 2018
Low frequency oscillation in an interconnected power system is becoming an increasingly serious problem. It is of great practical significance to make online evaluation of actual power grid’s stability. To evaluate the stability of the power system
Wenping Hu, Jifeng Liang, Yitao Jin, Fuzhang Wu, Xiaowei Wang, Ersong Chen   +5 more
doaj   +1 more source