Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Stabilization of grid frequency through dynamic demand control [PDF]
Frequency stability in electricity networks is essential to the maintenance of supply quality and security. This paper investigates whether a degree of built-in frequency stability could be provided by incorporating dynamic demand control into certain ...
Freris, Leon L. +2 more
core +4 more sources
Enhancing dynamic voltage stability in power systems with distributed generations [PDF]
Voltage stability is critical in the power distribution network. This paper aims to study the dynamic voltage stability problem. When wind generators reach maximum reactive power output, the bus voltage will operate near its steady-state stability limit.
Qitao Liu +2 more
openaire +2 more sources
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Transient stability sensitivity analysis of a simplified power system
There are many limits in power system operation however transient stability poses some of the most stringent limitations. Typical measures to assess transient stability, such as critical fault clearing time, provide some indication of whether or not a ...
H.M. Tan +3 more
core +1 more source
Power system instability prediction from the solution pattern of differential Riccati equations
Power system stability characteristics are typically evaluated in terms of small‐ and large‐signal (transient) stability. Access to the time‐varying A‐matrix of a state‐space‐based power systems model during transient conditions can be utilized to apply ...
J. Khodaparast +3 more
doaj +1 more source
Fast Stability of New Power System Based on a PMU Gradient Dynamic Deviation Method
The high proportion of renewable energy and power electronic equipment is emerging as a significant trend and key characteristic of the power system development driven by the dual promotion of the energy transformation and scientific technological ...
YU Miao, HU Jingxuan, ZHANG Shouzhi, WEI Jingjing, SUN Jianqun, WU Yixiao
doaj +1 more source
Advanced parallel classifier model for dynamic stability diagnosis in power system
Data for dynamic stable state in power system are very large. This leads to making difficult for a single classifier to learn boundaries of classes. This paper proposes a procedure to build Advanced Parallel Classifier Model (APCM) for dynamic stability ...
N.N. Au +3 more
doaj +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source

