Results 61 to 70 of about 18,229 (266)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Ground fault protection algorithm of active distribution network based on energy extremum direction

IET Generation, Transmission & Distribution
After large‐scale distributed power sources are connected to the distribution network, the fault current undergoes noticeable changes, affecting the accuracy of traditional single‐phase grounding fault algorithms.
Li Jun, He Min, Huang Shoudao, Wu Xuan, Fan lv, Liu Zhi Yong   +5 more
doaj   +1 more source

Effects of Direct-Quadrature Rotor Current Sensors’ Faults in Wind Energy Conversion System based on Doubly Fed Induction Generator

Electrica
This paper investigates the dynamic performance of a grid-connected wind energy conversion system (WECS) based on a doubly fed induction generator (DFIG) in the presence of additive and multiplicative faults in directquadrature rotor current sensors ...
Naziha Chouider, Karim Beddek, Rezki Haddouche, Mohamed Zerrougui, Omar Ramdani   +4 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

AC fault ride-through control strategy of MMC-UHVDC system with hierarchical connection mode

Frontiers in Energy Research
The ultra-high voltage direct current (UHVDC) transmission composed of modular multilevel converters (MMC) is an important technology for large-scale centralized transmission of renewable energy.
Mingli Ping, Mingli Ping, Chong Niu, Xinhe Liu, Meijuan Yang, Xianwei Wang   +5 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Fault current limiting system for 500-kV power systems

Electrical Engineering in Japan, 1997
Recently, expansion in the scale of power systems and development of localized power sources are leading to an increase in fault current of 500-kV systems. In the future, it is quite likely that the fault current at the interconnection of such power systems may exceed the rated short-time current of existing electric power facilities.
Shigeyuki Sugimoto, Junzo Kida, Hiroshi Arita, Chihiro Fukui, Tokio Yamagiwa, Yoshihiro Murai   +5 more
openaire   +2 more sources

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source