Results 61 to 70 of about 30,283 (308)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Application of the Analysis of Variance (ANOVA) in the Interpretation of Power Transformer Faults

open access: yes, 2022
Electrical power transformers are the most exorbitant and tactically prominent components of the South African electrical power grid. In contrast, they are burdened by internal winding faults predominantly on account of insulation system failure.
Bonginkosi A. Thango
core   +1 more source

Fast fault detection during power swing on a hybrid transmission line using WPT

open access: yesIET Generation, Transmission & Distribution, 2019
This paper presents a new technique for very high speed detection of fault during power swing on a hybrid transmission line consisting of an overhead line and an underground cable.
Bikash Patel, Parthasarathi Bera
doaj   +1 more source

CAUSES OF INDEFINITE FAULTS IN ESTONIAN 110 kV OVERHEAD POWER GRID; pp. 225–243 [PDF]

open access: yesOil Shale, 2013
The study considers causes of indefinite faults in the 110 kV over­head power grid in Estonia. The number of indefinite faults (flashovers on over­head line insulators) has increased significantly in the last years, causing a lot of problems to the ...
PAUL TAKLAJA   +3 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Desenvolvimento de um sistema de detecção e avaliação de faltas em geradores síncronos por meio do campo magnético externo [PDF]

open access: yes, 2014
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-Graduação em Engenharia Elétrica, Florianópolis, 2014.Esta tese apresenta o desenvolvido de um equipamento e de uma metodologia para detecção e análise de ...
Rigoni, Mauricio
core  

A high speed and sensitive protection for distribution network with DGs using ferrite rings as line boundary

open access: yesIET Generation, Transmission & Distribution
There exist problems of hard coordination and threshold setting as well as low sensitivity in overcurrent relay due to the bidirectional and small fault current when distributed generators are integrated into the distribution network.
Zhongxue Chang   +3 more
doaj   +1 more source

DISTRIBUTION ANALYSIS OF THE POWER SYSTEMS FAULTS [PDF]

open access: yesProblems of the Regional Energetics, 2013
In our days the significant number of power systems faults is taking place in power grids, being caused by various random factors. An in-depth analysis of these factors and of their distribution is needed in order to provide reliable forecasts and the ...
Popescu V.S.
doaj  

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Insulator defect detection with deep learning: A survey

open access: yesIET Generation, Transmission & Distribution, 2023
With the improvement of smart grid, utilizing unmanned aerial vehicles (UAV) to detect the operation status of insulators has attracted widespread attention.
Yue Liu   +3 more
doaj   +1 more source

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