Results 71 to 80 of about 1,755,988 (293)

Analysis of Dynamic Behaviour and Power Generation of a Wind-tidal System for Marine Environment [PDF]

open access: yes, 2012
This work presents the analysis of dynamic behaviour and power generation of a wind-tidal hybrid system. Mathematical models and system design approach were used to investigate the feasibility, reliability and economic impact of the system.
Ogbemhe, J.A.   +2 more
core  

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

Composite System Reliability Evaluation With Essential Reliability Services Assessment of Wind Power Integrated Power Systems

open access: yesIEEE Open Access Journal of Power and Energy, 2020
With the increasing penetration of renewable resources and the retirements of conventional coal-fired generation units, power systems are undergoing significant transformation with the instantaneous renewable generation penetration sometimes approaching ...
Yingying Wang   +3 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Multi-criteria decision-making approach for optimizing solar pv farms locations in Saudi Arabia with techno- economic considerations

open access: yesEnergy Reports
Site selection is essential for renewable energy projects due to climate effects such as soiling, average temperature, and average solar radiation. The proximity of the facilities, main roads, power line distributions, and the presence of the environment-
Majed A. Alotaibi   +2 more
doaj   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Experimental Study on the Dynamic Performance of Water-Lubricated Rubber Bearings with Local Contact

open access: yesShock and Vibration, 2018
Accurate dynamic characteristic coefficients of water-lubricated rubber bearings are necessary to research vibration of ship propulsion system. Due to mixed lubrication state of water-lubricated rubber bearings, normal test rig and identification method ...
Wu Ouyang   +3 more
doaj   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

An economic analysis of a commercial approach to the design and fabrication of a space power system [PDF]

open access: yes
A commercial approach to the design and fabrication of an economical space power system is presented. Cost reductions are projected through the conceptual design of a 2 kW space power system built with the capability for having serviceability.
Been, J. F., Putney, Z.
core   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

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