Results 61 to 70 of about 408,903 (311)

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

A Non-Intrusive Thermal Fault Inversion Method for GIS Using a POD-Kriging Surrogate Model and the Grey Wolf Optimizer

open access: yesEnergies
To address the inverse identification of contact-related thermal faults in gas-insulated switchgear (GIS), this study proposes a method for contact resistance inversion and internal temperature field reconstruction.
Linhong Yue   +4 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

A conditionally constrained compound sub‐gradient method for distributed energy coordination

open access: yesIET Generation, Transmission & Distribution, 2023
A conditionally constrained compound (CCC) sub‐gradient method typically involves solutions by multi‐agents, which have important applications in distributed energy resources (DER).
Xu Jie, Sizhou Sun
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Identifying high-impact operating states in power system reliability analysis [PDF]

open access: yes, 2018
The reliability of a power system depends, among other things, on the operating states of the system. For reliability analysis for long-term planning purposes, it may be necessary to consider a large set of representative operating states, and clustering
Iver Bakken Sperstad   +1 more
core   +1 more source

Losses analysis of soft magnetic ring core under sinusoidal pulse width modulation (SPWM) and space vector pulse width modulation (SVPWM) excitations

open access: yesAIP Advances, 2018
Practical core losses in electrical machines differ significantly from those experimental results using the standardized measurement method, i.e. Epstein Frame method.
Hezhe Gao   +6 more
doaj   +1 more source

Power system reliability enhancement by using PowerformerTM [PDF]

open access: yesSerbian Journal of Electrical Engineering, 2009
A high-voltage generator PowerformerTM is a new generation of the AC generators. The most significant advantages of these PowerformerTM are their direct connection to high-voltage grid, higher availability, and more reactive power margin, short term ...
Rahmat-Allah Hooshmand   +2 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Power system reliability analysis

open access: yesIOP Conference Series: Earth and Environmental Science, 2020
Abstract Electric power development is the key factor of economic development, but also an important guarantee of industrial modernization. At present, with the improvement of people’s quality of life, electricity has become an indispensable part of ensuring people’s lives.
Xiwen Feng, Fei Tong
openaire   +1 more source

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