Results 51 to 60 of about 408,903 (311)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1513-1534, June 2026.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

A Transformer Maintenance Interval Optimization Method Considering Imperfect Maintenance and Dynamic Maintenance Costs

open access: yesApplied Sciences
As one of the most critical components of the power grid system, transformer maintenance strategy planning significantly influences the safe, economical, and sustainable operation of the power system. Periodic imperfect maintenance strategies have become
Jianzhong Yang   +6 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Reliability Assessment for Tie Line Capacity Assistance of Power Systems Based on Multi-Agent System

open access: yes, 2014
Technological developments in industrial innovations have currently been related to interconnected system assistance and distribution networks. This important in order to enable an electrical load to continue receive power in the event of disconnection
Shalash, Nadheer A.   +3 more
core   +1 more source

A bi-level operational reliability evaluation model for power systems considering economic dispatch and demand response

open access: yesInternational Journal of Electrical Power & Energy Systems
The increasing deregulation and integration of renewable energy are contributing to growing uncertainties in the power systems. The main uncertainties include the equilibrium game process among different stakeholders, the uncertainty of renewable ...
Congcong Pan   +6 more
doaj   +1 more source

A weather-based power distribution system reliability assessment

open access: yesAlexandria Engineering Journal, 2023
The continuity of power supply is affected by many factors; the weather conditions to which power system components are exposed are considered the most effect.
Hani A. Aldhubaib   +2 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Reliability and vulnerability analyses of critical infrastructures: Comparing two approaches in the context of power systems

open access: yes, 2013
Society depends on services provided by critical infrastructures, and hence it is important that they are reliable and robust. Two main approaches for gaining knowledge required for designing and improving critical infrastructures are reliability ...
Hassel, Henrik,   +3 more
core   +1 more source

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