Results 61 to 70 of about 2,662,256 (336)

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

An optimisation method of whole‐process restoration decision‐making of power systems considering disturbance‐resisting ability of the restored network

IET Generation, Transmission & Distribution, 2023
Disturbance‐resisting ability (DRA) of the restored network needs to be considered when making a restoration scheme of power systems, to ensure system security and reduce secondary blackout risk.
Xueping Gu, Yansong Bai, Shaoyan Li, Ke Liu, Yutian Liu, Hongtao Wang   +5 more
doaj   +1 more source

An online decision-making method based on multi-agent interaction for coordinated load restoration

Frontiers in Energy Research, 2022
Load restoration coordinating transmission grid, distribution grid, and microgrids is an effective measure that is taken into consideration while improving the power system resilience in extreme weather conditions.
Rui Fan, Runjia Sun, Yutian Liu, Rizwan ul Hassan   +3 more
doaj   +1 more source

Exploiting multi-agent system technology within an autonomous regional active network management system [PDF]

, 2007
This paper describes the proposed application of multi-agent system (MAS) technology within AuRA-NMS, an autonomous regional network management system currently being developed in the UK through a partnership between several UK universities, distribution
Davidson, Euan M., McArthur, Stephen D. J.   +1 more
core   +1 more source

Power System Restoration Planning Strategy Based on Optimal Energizing Time of Sectionalizing Islands

, 2018
Common power system restoration planning strategy is based on a ‘build up’ approach, where a blackout system is sectionalized among several islands for parallel restoration prior to resynchronization.
D. N. A. Talib, H. Mokhlis, M. S. A. Talip, K. Naidu, H. Suyono   +4 more
semanticscholar   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Analysis and Explanation of Resonant Phenomena Involving EHV Transformers during Power System Restoration Tests

Energies, 2023
This paper deals with the simulation and the experimental confirmation of electromagnetic events that could interfere with the successful formation of the restoration path during the power system restoration procedure.
Roberto Benato, Sebastian Dambone Sessa, Giorgio Maria Giannuzzi, Cosimo Pisani, Michele Poli, Francesco Sanniti   +5 more
doaj   +1 more source

Risks in the European Transmission System and a Novel Restoration Strategy for a Power System after a Major Blackout

Applied Sciences, 2022
Many citizens of European countries may soon experience a long and extensive blackout. The lack of predictability in the output of renewable energy sources, aggravating the problem of consistently matching supply with demand on electric grids, along with
G. Fotis, V. Vita, T. Maris
semanticscholar   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Development of a Sequential Restoration Strategy Based on the Enhanced Dijkstra Algorithm for Korean Power Systems

Applied Sciences, 2016
When a blackout occurs, it is important to reduce the time for power system restoration to minimize damage. For fast restoration, it is important to reduce taking time for the selection of generators, transmission lines and transformers.
Bokyung Goo, Solyoung Jung, Jin Hur
doaj   +1 more source