Results 41 to 50 of about 18,308,647 (297)
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Equity‐aware power distribution system restoration
IET Generation, Transmission & DistributionThe efficient, reliable, and resilient supply of electricity has become essential for social and economic well‐being of the modern society. However, more frequent occurrence of extreme weather events has exposed inequity in the planning and operation ...
Luis Rodriguez‐Garcia +2 more
doaj +1 more source
Optimized dispatch of wind farms with power control capability for power system restoration
Journal of Modern Power Systems and Clean Energy, 2017 As the power control technology of wind farms develops, the output power of wind farms can be constant, which makes it possible for wind farms to participate in power system restoration.
Yunyun Xie +5 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Optimal Power Systems Restoration Based on Energy Quality and Stability Criteria
Energies, 2022 Electric power systems (EPS) are exposed to disconnections of their elements, such as transmission lines and generation units, due to meteorological factors or electrical failures.
Francisco Quinteros +2 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Strategic Planning for Power System Restoration [PDF]
Vulnerability, Uncertainty, and Risk, 2011 This paper considers the power system restoration planning problem (PSRPP) for disaster recovery, a fundamental problem faced by all populated areas. PSRPPs are complex stochastic optimization problems that combine resource allocation, warehouse location, and vehicle routing considerations.
Carleton Coffrin +2 more
openaire +3 more sources
A Multi-Agent Approach to Power System Restoration
IEEJ Transactions on Power and Energy, 2001 This paper proposes a multi-agent approach to power system restoration. The proposed system consists of several bus agents (BAGs) and a single facilitator agent (FAG). A BAG is developed to decide a sub-optimal target configuration after faults occur by interacting with other BAGs, while a FAG is developed to act as a manager for the decision process ...
T. Nagata +3 more
openaire +2 more sources