Results 61 to 70 of about 582,882 (296)

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

Optimizing Service Restoration in Distribution Systems with Uncertain Repair Time and Demand [PDF]

, 2018
This paper proposes a novel method to co-optimize distribution system operation and repair crew routing for outage restoration after extreme weather events. A two-stage stochastic mixed integer linear program is developed.
Arif, Anmar, Chen, Chen, Ma, Shanshan, Ryan, Sarah, Ryan, Sarah, Wang, Jianhui, Wang, Zhaoyu   +6 more
core   +3 more sources

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Dynamic restoration electricity price optimization method to enhance the resilience of distribution networks with multiple‐microgrids

IET Generation, Transmission & Distribution
Resilience is one of the main features of smart distribution networks, and a microgrid (MG) access to the distribution network provides an effective way to improve resilience.
Hongkun Wang, Yujie Gao, Hong Zhang, Dongmei Yan, Hongwei Li   +4 more
doaj   +1 more source

A Restoration Method for Distribution System Based on Projection of Multiple Microgrids

Zhongguo dianli
The participation of microgrids in distribution system restoration can improve the restoration effects and thereby enhance the system resilience. A restoration method for distribution system with multiple microgrids is proposed, which considers the ...
Shiyan ZHU, Yin XU, Jinghan HE, Ying WANG   +3 more
doaj   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Software defined networking: meeting carrier grade requirements [PDF]

, 2011
Software Defined Networking is a networking paradigm which allows network operators to manage networking elements using software running on an external server.
Colle, Didier, Demeester, Piet, Pickavet, Mario, Sharma, Sachin, Staessens, Dimitri   +4 more
core   +2 more sources

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Identification of Acceptable Restoration Strategies [PDF]

Journal of Systemics, Cybernetics and Informatics, 2008
In recent years, we have seen several catastrophic and cascading failures of power systems throughout the world. Power system breakup and blackouts are rare events.
Seung-Tae Cha, Nam-Ho Lee, Eung-Bo Shim, Jeong-Hoon Shin, Hyun-Il Son, Soo-Chul Nam   +5 more
doaj  

Optimal distribution system restoration using PHEVs

IET Smart Grid, 2018
Power outages cost billions of dollars every year and jeopardise the lives of hospital patients. Traditionally, power distribution system takes a long time to recover after a major blackout, due to its top-down operation strategy.
Wei Sun, Nemica Kadel, Inalvis Alvarez-Fernandez, Reza Roofegari Nejad, Amir Golshani   +4 more
doaj   +1 more source