Results 91 to 100 of about 133,467 (304)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

A comparative simulative study to determine controller schemes of static var compensator (svc) for stability of power system

open access: yesMehran University Research Journal of Engineering and Technology
A key challenge in ensuring and maintaining power system stability is the rapid management of power transients. These voltage fluctuations arise from various causes, such as sudden load changes or network faults, which, if not addressed quickly, can lead
Osama Butt   +4 more
doaj   +1 more source

Digital computer study of nuclear reactor thermal transients during startup of 60-kWe Brayton power conversion system [PDF]

open access: yes
A digital computer study was made of reactor thermal transients during startup of the Brayton power conversion loop of a 60-kWe reactor Brayton power system.
Jefferies, K. S., Tew, R. C.
core   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Modeling of power electronic systems with EMTP [PDF]

open access: yes
In view of the potential impact of power electronics on power systems, there is need for a computer modeling/analysis tool to perform simulation studies on power systems with power electronic components as well as to educate engineering students about ...
Dravid, Narayan V., Tam, Kwa-Sur
core   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

open access: yesFEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee   +6 more
wiley   +1 more source

Experimental investigation of reactor-loop transients during SNAP-8 power conversion system startup [PDF]

open access: yes
Experimental investigation of reactor loop transients during SNAP 8 power conversion system ...
Jefferies, K. S.
core   +1 more source

Remote Monitoring in Myasthenia Gravis: Exploring Symptom Variability

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare, autoimmune disorder characterized by fluctuating muscle weakness and potential life‐threatening crises. While continuous specialized care is essential, access barriers often delay timely interventions. To address this, we developed MyaLink, a telemedical platform for MG patients.
Maike Stein   +13 more
wiley   +1 more source

Measurement of control system response using an analog operational circuit [PDF]

open access: yes
Ten basic steps are established for an analog method that measures control system response parameters. An example shows how these steps were used on a speed control portion of an auxiliary power unit.
Lalli, V. R.
core   +1 more source

Patterns of Postictal Abnormalities in Relation to Status Epilepticus in Adults

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Abnormalities on peri‐ictal diffusion‐weighted magnetic resonance imaging (DWI‐PMAs) are well‐established for patients with status epilepticus (SE), but knowledge on patterns of DWI‐PMAs and their prognostic impact is sparse. Methods This systematic review and individual participant data meta‐analysis included observational studies ...
Andrea Enerstad Bolle   +11 more
wiley   +1 more source

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