Results 71 to 80 of about 133,467 (304)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Improving primary frequency response in networked microgrid operations using multilayer perceptron-driven reinforcement learning

IET Smart Grid, 2020
Individual microgrids can improve the reliability of power systems during extreme events, and networked microgrids can further improve efficiency through resource sharing and increase the resilience of critical end-use loads. However, networked microgrid
Nikitha Radhakrishnan, Indrasis Chakraborty, Indrasis Chakraborty, Jing Xie, Priya Thekkumparambath Mana, Francis K. Tuffner, Bishnu P. Bhattarai, Bishnu P. Bhattarai, Kevin P. Schneider   +8 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Comprehensive Real-Time Hardware-In-the-Loop Transient Emulation of MVDC Power Distribution System on Nuclear Submarine

IEEE Open Journal of the Industrial Electronics Society, 2020
A nuclear submarine has significant performance advantages over the conventional dieselelectric submarine. Its powerful nuclear propulsion can be operated independently of air and does not require refueling throughout the 25-year life span.
Weiran Chen, Tian Liang, Venkata Dinavahi   +2 more
doaj   +1 more source

Control based power smoothing for aggregated vertical axis wind turbines [PDF]

, 2012
Recently there has been renewed interest in the potential of vertical axis wind turbines (VAWTs), particularly, at very large scale of 10 MW or above owing to their structural simplicity.
Leithead, William, Soraghan, Conaill Eoin, Yue, Hong   +2 more
core  

A method of detecting radio transients [PDF]

, 2010
Radio transients are sporadic signals and their detection requires that the backends of radio telescopes be equipped with the appropriate hardware and software to undertake this.
Basseville, Bradley, Cordes, Cordes, Cordes, Duda, Eadie, Fridman, Hawkins, Illingworth, Jarque, Lorden, McLaughlin, P. A. Fridman, Page, Rao, Shiryaev, Van Dobben de Bruyn, Wald, Wang, Whalen   +20 more
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Experimental investigation of reactor-loop transients during startup of a simulated SNAP-8 system [PDF]

Primary loop transients during startup of Rankine cycle space power system in SNAP 8 ...
Block, H. B., Jefferies, K. S., Thollot, P. A.   +2 more
core   +1 more source

The hard quiescent spectrum of the neutron-star X-ray transient EXO 1745-248 in the globular cluster Terzan 5

, 2003
We present a Chandra observation of the globular cluster Terzan 5 during times when the neutron-star X-ray transient EXO 1745-248 located in this cluster was in its quiescent state.
Edmonds, Peter D., Grindlay, Jonathan E., Heinke, Craig O., Jonker, Peter G., Lewin, Walter H. G., Miller, Jon M., Pooley, David, Wijnands, Rudy   +7 more
core   +3 more sources

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source