Results 51 to 60 of about 25,852 (310)

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Magnetic core effects on the high-frequency behavior of transformers

International Journal of Electrical Power & Energy Systems
This paper investigates the high-frequency transformer losses attributed to eddy currents in both conductors and the core. A comprehensive model of a transformer winding is presented, meticulously incorporating skin and proximity effects.
Farzad Nasirpour, Mohamad Ghaffarian Niasar, Marjan Popov   +2 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Blackstart from HVDC‐connected offshore wind: Hard versus soft energization

IET Renewable Power Generation, 2021
In recent years, renewable energy sources have been integrated on a large scale in power systems all around the world to address the environmental sustainability concerns.
Anubhav Jain, Oscar Saborío‐Romano, Jayachandra N. Sakamuri, Nicolaos A. Cutululis   +3 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Abrupt change detection in power system fault analysis using wavelet transform

, 2005
This paper describes the application of the wavelets used to detect the abrupt changes in the signals recorded during disturbances in the electrical power network in South Africa. Main focus has been to estimate exactly the timeinstants of the changes in
Zivanovic, R, Ukil, Abhisek
core   +1 more source

DC protection coordination for multi‐terminal HB‐MMC‐based HVDC grids

IET Renewable Power Generation
Fast progress of High Voltage Direct Current (HVDC) technology has been considerable over the past decades. Emerging Modular Multilevel Converter (MMC) provides power systems with promising solutions to integrate large‐scale renewable energy sources, as ...
Seyed Hassan Ashrafi Niaki, Zhe Chen, Birgitte Bak‐Jensen, Kamran Sharifabadi, Zhou Liu, Shuju Hu   +5 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Investigation of Automatic Transient Classification Method for Pressurized Water Reactor Nuclear Power Plant

Yuanzineng kexue jishu, 2023
Transient statistics is a significant process in nuclear power plant, and is closely related to the operation monitoring and life extension of nuclear power plant.
BAI Xiaoming1;YU Xinyang1;CAO Guochang2;LI Zheng1;CAO Hongsheng2;CUI Huaiming1;AI Honglei1;XIONG Furui1;JIANG He2
doaj   +1 more source