Results 101 to 110 of about 14,866,455 (294)

Extrapolation of cavitation and hydrodynamic pressure in lubricated contacts: a physics-informed neural network approach

Advanced Modeling and Simulation in Engineering Sciences
A comprehensive understanding of the dynamics of tribological interactions is essential for enhancing efficiency and durability in a multitude of technical domains.
Faras Brumand-Poor, Freddy Kokou Azanledji, Nils Plückhahn, Florian Barlog, Lukas Boden, Katharina Schmitz   +5 more
doaj   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Protection of MVDC shipboard power system using Rogowski coil

, 2016
One of the major challenges faced in the design of DC shipboard power systems (SPS) is the provision of effective DC protection. The selection of the current sensors plays an important role in the detection of fault current in DC systems.
Satpathi, K, Ukil, Abhisek, Kuntal Satpathi, Satpathi, Kuntal, Abhisek Ukil, Ukil, A   +5 more
core   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Real-time System-wide Inertia Estimation in Power Systems with High Wind Penetration Levels [PDF]

, 2016
11th International Workshop on Large-Scale Integration of Wind Power into Power Systems as well as on Transmission Networks for Offshore Wind Power Plants, Lisbon, Portugal, 13-15 November 2012Knowledge of on-line inertia in power systems with high and ...
Power, Michael, Bank Tavakoli, M. Reza, Ruttledge, Lisa, Flynn, Damian   +3 more
core   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

FEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés, Luise Franz, Christian P.R. Hackenberger   +2 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Point of collapse methods applied to AC/DC power systems

, 2002
(© 1992 IEEE) Canizares, C. A., Alvarado, F. L., DeMarco, C. L., Dobson, I., & Long, W. F. (1992). Point of collapse methods applied to AC/DC Power Systems. IEEE Transactions on Power Systems, 7(2), 673–683.
DeMarco, Christopher L., Canizares, Claudio A., Alvarado, Fernando L., Long, Willis F., Dobson, I.an   +4 more
core   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source