Results 101 to 110 of about 3,527,589 (300)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Power Performance of the Combined Monopile Wind Turbine and Floating Buoy with Heave-type Wave Energy Converter

open access: yesPolish Maritime Research, 2019
This study deals with a new concept of near-shore combined renewable energy system which integrates a monopile wind turbine and a floating buoy with heave-type wave energy converter( WEC). Wave energy is absorbed by power-take-off (PTO) systems.
Homayoun Esmaeil   +2 more
doaj   +1 more source

Design, Construction and Testing of a Hydraulic Power Take-Off for Wave Energy Converters

open access: yesEnergies, 2012
This paper presents the construction, mathematical modeling and testing of a scaled universal hydraulic Power Take-Off (PTO) device for Wave Energy Converters (WECs). A specific prototype and test bench were designed and built to carry out the tests. The
Joseba Lasa   +5 more
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Low power LVDS transceiver for AER links with burst mode operation capability [PDF]

open access: yes, 2009
This paper presents the design and simulation of an LVDS transceiver intended to be used in serial AER links. Traditional implementations of LVDS serial interfaces require a continuous data flow between the transmitter and the receiver to keep the ...
Linares Barranco, Bernabé   +2 more
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Performance of arrays of direct-driven wave energy converters under optimal power take-off damping

open access: yesAIP Advances, 2016
It is well known that the total power converted by a wave energy farm is influenced by the hydrodynamic interactions between wave energy converters, especially when they are close to each other. Therefore, to improve the performance of a wave energy farm,
Liguo Wang   +3 more
doaj   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Predictive Modelling and Optimisation of Power Generation for the M4 Wave Energy Converter: A Deep Learning Approach

open access: yesInternational Marine Energy Journal
This paper investigates the use of a nonlinear autoregression neural network for wave field predictions, and its implementation into a power-take off passive loading control system which tunes the damping coefficient for a wave energy converter.
Samantha Hoekstra   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy